Molecular biology of atherosclerosis

PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

High-density lipoproteins: a consensus statement from the National Lipid Association

PP Toth, PJ Barter, RS Rosenson, WE Boden… - Journal of clinical …, 2013 - Elsevier
For> 4 decades it has been recognized that elevated serum levels of high-density
lipoprotein cholesterol (HDL-C) are associated with reduced risk of cardiovascular disease …

Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey

R Kones - Drug design, development and therapy, 2011 - Taylor & Francis
A recent explosion in the amount of cardiovascular risk and incipient, undetected subclinical
cardiovascular pathology has swept across the globe. Nearly 70% of adult Americans are …

The emerging role of HDL in glucose metabolism

BG Drew, KA Rye, SJ Duffy, P Barter… - Nature Reviews …, 2012 - nature.com
A low plasma level of HDL cholesterol is an atherosclerotic risk factor; however, emerging
evidence suggests that low HDL levels might also contribute to the pathophysiology of type …

Extracellular vesicles as emerging targets in cancer: Recent development from bench to bedside

K Wu, F Xing, SY Wu, K Watabe - … et Biophysica Acta (BBA)-Reviews on …, 2017 - Elsevier
Extracellular vesicles (EVs) have emerged as important players of cancer initiation and
progression through cell-cell communication. They have been recognized as critical …

The role of propolis in oxidative stress and lipid metabolism: a randomized controlled trial

V Mujica, R Orrego, J Pérez, P Romero… - Evidence‐Based …, 2017 - Wiley Online Library
Although there is evidence of the benefits of propolis on human health, the vast majority of
studies have been conducted using animal models. The present study includes the chemical …

Molecular sources of residual cardiovascular risk, clinical signals, and innovative solutions: relationship with subclinical disease, undertreatment, and poor adherence …

R Kones - Vascular Health and Risk Management, 2013 - Taylor & Francis
Residual risk, the ongoing appreciable risk of major cardiovascular events (MCVE) in statin-
treated patients who have achieved evidence-based lipid goals, remains a concern among …

The lipidomic profile of the nanoparticle-biomolecule corona reflects the diversity of plasma lipids

L Papafilippou, A Nicolaou, AC Kendall… - Nanoscale, 2023 - pubs.rsc.org
The spontaneous self-assembly of biomolecules around the surface of nanoparticles (NPs)
once exposed to plasma and other biofluids, has been termed the 'biomolecule corona' …

Inflammation and atherosclerosis: direct versus indirect mechanisms

ME Rosenfeld - Current opinion in pharmacology, 2013 - Elsevier
It is now widely accepted that the development of atherosclerotic lesions involves a chronic
inflammatory response that includes both innate and adaptive immune mechanisms …

Paraoxonase 1 and HDL maturation

A Gugliucci, T Menini - Clinica chimica acta, 2015 - Elsevier
Understanding the kinetics and function of paraoxonase 1 (PON1) is becoming an important
issue in atherosclerosis. Low PON1 activity has been consistently linked with an increased …