Cytosine methylation in mammals is an epigenetic modification required for viability of the
developing embryo. It has been suggested that DNA methylation plays important roles in X …

Psychiatric disease is believed to result from a combination of genetic vulnerability and
environmental influence. At the crux are epigenetic modifications, which mediate the …

DNA methylation is essential for normal embryonic development. Distinctive genomic
methylation patterns must be formed and maintained with high fidelity to ensure the …

Ectopic secretion of ACTH, from sites such as small cell lung cancer (SCLC), results in
severe Cushing's syndrome. ACTH is cleaved from POMC. The syndrome may occur when …

Administration of the heavy metal cadmium (Cd) induces ventral body wall defects (VBWD)
in the chick embryo. In this model, the expression of most genes involved in body wall …

Several studies have examined associations between peripheral DNA methylation patterns
of the serotonin transporter gene (SLC6A4) promoter and symptoms of depression and …

To analyse the biological role of 5‐methylation of cytosine residues in DNA requires precise
and efficient methods for detecting individual 5‐methylcytosines (5‐MeCs) in genomic DNA …

Leptin is a master regulator of energy homeostasis. Its expression, prevalently localized in
adipocytes, is positively related to adipose mass. Epigenetics is emerging as an important …

Studies in rodents, nonhuman primates, and humans suggest that epigenetic processes
mediate between early life experiences and adult phenotype. However, the normal evolution …

Gene expression from the Moloney murine leukemia retrovirus (Mo-MuLV) is highly
restricted in embryonic carcinoma (EC) and embryonic stem (ES) cells. We compared levels …