Therapeutic potential of mesenchymal stem/stromal cell-derived secretome and vesicles for lung injury and disease
A Liu, X Zhang, H He, L Zhou, Y Naito… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: The acute respiratory distress syndrome (ARDS) is a devastating clinical
condition common in patients with respiratory failure. Based largely on numerous preclinical …
condition common in patients with respiratory failure. Based largely on numerous preclinical …
[HTML][HTML] Adipose-derived mesenchymal stem cells: a promising tool in the treatment of musculoskeletal diseases
M Torres-Torrillas, M Rubio, E Damia, B Cuervo… - International Journal of …, 2019 - mdpi.com
Chronic musculoskeletal (MSK) pain is one of the most common medical complaints
worldwide and musculoskeletal injuries have an enormous social and economical impact …
worldwide and musculoskeletal injuries have an enormous social and economical impact …
Adipose-derived mesenchymal stem cells in autoimmune disorders: state of the art and perspectives for systemic sclerosis
Mesenchymal stromal/stem cells (MSC) are non-hematopoietic multipotent progenitor cells,
first described in bone marrow in the middle of last century. Since then, MSC have been the …
first described in bone marrow in the middle of last century. Since then, MSC have been the …
[HTML][HTML] Production of mesenchymal stem cells through stem cell reprogramming
A Abdal Dayem, SB Lee, K Kim, KM Lim… - International journal of …, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) possess a broad spectrum of therapeutic applications and
have been used in clinical trials. MSCs are mainly retrieved from adult or fetal tissues …
have been used in clinical trials. MSCs are mainly retrieved from adult or fetal tissues …
[HTML][HTML] Extracellular vesicles in lung health, disease, and therapy
MJ McVey, M Maishan, KEC Blokland… - … of Physiology-Lung …, 2019 - journals.physiology.org
Both physiological homeostasis and pathological disease processes in the lung typically
result from complex, yet coordinated multicellular responses that are synchronized via …
result from complex, yet coordinated multicellular responses that are synchronized via …
Mesenchymal stem cell therapy protects lungs from radiation-induced endothelial cell loss by restoring superoxide dismutase 1 expression
D Klein, J Steens, A Wiesemann, F Schulz… - Antioxidants & redox …, 2017 - liebertpub.com
Aims: Radiation-induced normal tissue toxicity is closely linked to endothelial cell (EC)
damage and dysfunction (acute effects). However, the underlying mechanisms of radiation …
damage and dysfunction (acute effects). However, the underlying mechanisms of radiation …
Antifibrotic, antioxidant, and immunomodulatory effects of mesenchymal stem cells in HOCl‐induced systemic sclerosis
ATJ Maria, K Toupet, C Bony, N Pirot… - Arthritis & …, 2016 - Wiley Online Library
Objective Systemic sclerosis (SSc) is a rare intractable disease with unmet medical need
and fibrosis‐related mortality. Absence of efficient treatments has prompted the development …
and fibrosis‐related mortality. Absence of efficient treatments has prompted the development …
[HTML][HTML] Paracrine factors from mesenchymal stem cells attenuate epithelial injury and lung fibrosis
Q Shen, B Chen, Z Xiao, L Zhao… - Molecular …, 2015 - spandidos-publications.com
Paracrine factors are currently considered to be the major mechanism through which
mesenchymal stem cells (MSCs) exert their actions. The aim of this study was to investigate …
mesenchymal stem cells (MSCs) exert their actions. The aim of this study was to investigate …
Current strategies to generate human mesenchymal stem cells in vitro
J Steens, D Klein - Stem cells international, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) are heterogeneous multipotent stem cells that are involved
in the development of mesenchyme‐derived evolving structures and organs during …
in the development of mesenchyme‐derived evolving structures and organs during …
[HTML][HTML] Cell-based therapy for idiopathic pulmonary fibrosis
Q Lu, AHK El-Hashash - Stem cell investigation, 2019 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is an example of interstitial lung diseases that is
characterized by chronic, progressive, and fibrotic lung injuries. During lung fibrosis, normal …
characterized by chronic, progressive, and fibrotic lung injuries. During lung fibrosis, normal …