Charting the evolution of chemoenzymatic strategies in the syntheses of complex natural products
CN Stout, NM Wasfy, F Chen… - Journal of the American …, 2023 - ACS Publications
Bolstered by recent advances in bioinformatics, genetics, and enzyme engineering, the field
of chemoenzymatic synthesis has enjoyed a rapid increase in popularity and utility. This …
of chemoenzymatic synthesis has enjoyed a rapid increase in popularity and utility. This …
Immobilisation and application of lipases in organic media
P Adlercreutz - Chemical Society Reviews, 2013 - pubs.rsc.org
Different methods of preparing lipases for use in organic media are critically reviewed. Solid
lipase preparations can be made by typical immobilisation methods such as adsorption …
lipase preparations can be made by typical immobilisation methods such as adsorption …
Stereoselective cyclopropanation reactions
H Lebel, JF Marcoux, C Molinaro… - Chemical Reviews, 2003 - ACS Publications
Organic chemists have always been fascinated by the cyclopropane subunit. 1 The smallest
cycloalkane is found as a basic structural element in a wide range of naturally occurring …
cycloalkane is found as a basic structural element in a wide range of naturally occurring …
Recent developments in ring opening polymerization of lactones for biomedical applications
AC Albertsson, IK Varma - Biomacromolecules, 2003 - ACS Publications
Aliphatic polyesters prepared by ring-opening polymerization of lactones are now used
worldwide as bioresorbabale devices in surgery (orthopaedic devices, sutures, stents, tissue …
worldwide as bioresorbabale devices in surgery (orthopaedic devices, sutures, stents, tissue …
Bacterial biocatalysts: molecular biology, three-dimensional structures, and biotechnological applications of lipases
KE Jaeger, BW Dijkstra, MT Reetz - Annual Reviews in …, 1999 - annualreviews.org
▪ Abstract Bacteria produce and secrete lipases, which can catalyze both the hydrolysis and
the synthesis of long-chain acylglycerols. These reactions usually proceed with high …
the synthesis of long-chain acylglycerols. These reactions usually proceed with high …
Organic solvent tolerant lipases and applications
S Sharma, SS Kanwar - The Scientific World Journal, 2014 - Wiley Online Library
Lipases are a group of enzymes naturally endowed with the property of performing reactions
in aqueous as well as organic solvents. The esterification reactions using lipase (s) could be …
in aqueous as well as organic solvents. The esterification reactions using lipase (s) could be …
[图书][B] Hydrolases in organic synthesis: regio-and stereoselective biotransformations
UT Bornscheuer, RJ Kazlauskas - 2006 - books.google.com
From reviews to the first edtion:" Bornscheuer and Kazlauskas have set out, and succeeded,
in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and …
in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and …
Enzymatic polymerization
S Kobayashi, H Uyama, S Kimura - Chemical reviews, 2001 - ACS Publications
There has been an exponential increase in interest in the area of in vitro enzyme-catalyzed
organic reactions, since many families of enzymes can be utilized for transformation of not …
organic reactions, since many families of enzymes can be utilized for transformation of not …
Synthesis of chiral cyclopentenones
SP Simeonov, JPM Nunes, K Guerra… - Chemical …, 2016 - ACS Publications
The cyclopentenone unit is a very powerful synthon for the synthesis of a variety of bioactive
target molecules. This is due to the broad diversity of chemical modifications available for …
target molecules. This is due to the broad diversity of chemical modifications available for …
Asymmetric organocatalysis
H Pellissier - Tetrahedron, 2007 - Elsevier
The enantioselective production of compounds is a central theme in current research. The
broad utility of synthetic chiral molecules as single-enantiomer pharmaceuticals, in …
broad utility of synthetic chiral molecules as single-enantiomer pharmaceuticals, in …