[HTML][HTML] Balancing Immune Protection and Immune Pathology by CD8+ T-Cell Responses to Influenza Infection
Influenza A virus (IAV) is a significant human pathogen causing annual epidemics and
periodic pandemics. CD8+ cytotoxic T lymphocyte (CTL)-mediated immunity contributes to …
periodic pandemics. CD8+ cytotoxic T lymphocyte (CTL)-mediated immunity contributes to …
T cell mediated immunity to influenza: mechanisms of viral control
NL La Gruta, SJ Turner - Trends in immunology, 2014 - cell.com
Infection with influenza A virus (IAV) is a major cause of worldwide morbidity and mortality.
Recent findings indicate that T cell immunity is key to limiting severity of disease arising from …
Recent findings indicate that T cell immunity is key to limiting severity of disease arising from …
Viral infection of the lung: host response and sequelae
JK Yoo, TS Kim, MM Hufford, TJ Braciale - Journal of allergy and clinical …, 2013 - Elsevier
Because of its essential role in gas exchange and oxygen delivery, the lung has evolved a
variety of strategies to control inflammation and maintain homeostasis. Invasion of the lung …
variety of strategies to control inflammation and maintain homeostasis. Invasion of the lung …
[HTML][HTML] Plasmacytoid dendritic cells and cancer immunotherapy
C Fu, L Zhou, QS Mi, A Jiang - Cells, 2022 - mdpi.com
Despite largely disappointing clinical trials of dendritic cell (DC)-based vaccines, recent
studies have shown that DC-mediated cross-priming plays a critical role in generating anti …
studies have shown that DC-mediated cross-priming plays a critical role in generating anti …
Dendritic cell-based vaccines against cancer: challenges, advances and future opportunities
As the most potent professional antigen presenting cells, dendritic cells (DCs) have the
ability to activate both naive CD4 and CD8 T cells. Recognized for their exceptional ability to …
ability to activate both naive CD4 and CD8 T cells. Recognized for their exceptional ability to …
Lung CD103+ dendritic cells efficiently transport influenza virus to the lymph node and load viral antigen onto MHC class I for presentation to CD8 T cells
The uptake, transport, and presentation of Ags by lung dendritic cells (DCs) are central to the
initiation of CD8 T cell responses against respiratory viruses. Although several studies have …
initiation of CD8 T cell responses against respiratory viruses. Although several studies have …
Origin and functional heterogeneity of non‐lymphoid tissue dendritic cells in mice
Dendritic cells (DCs) have been extensively studied in mice lymphoid organs, but less is
known about the origin and the mechanisms that regulate DC development and function in …
known about the origin and the mechanisms that regulate DC development and function in …
Innate immune sensing and response to influenza
B Pulendran, MS Maddur - Influenza Pathogenesis and Control-Volume II, 2015 - Springer
Influenza viruses pose a substantial threat to human and animal health worldwide. Recent
studies in mouse models have revealed an indispensable role for the innate immune system …
studies in mouse models have revealed an indispensable role for the innate immune system …
Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors
M Cabeza-Cabrerizo, J van Blijswijk, S Wienert… - Science …, 2019 - science.org
Conventional dendritic cells (cDCs) are found in all tissues and play a key role in immune
surveillance. They comprise two major subsets, cDC1 and cDC2, both derived from …
surveillance. They comprise two major subsets, cDC1 and cDC2, both derived from …
Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses
Plasmacytoid dendritic cells (pDCs) are a rare population of circulating cells that selectively
express Toll‐like receptors (TLR) 7 and TLR9 and have the capacity to produce large …
express Toll‐like receptors (TLR) 7 and TLR9 and have the capacity to produce large …