Purpose To investigate the effect of prolonged glucocorticoid treatment for patients with
acute respiratory distress syndrome (ARDS). Methods We conducted two sets of intention-to …

Innate immunity normally provides excellent defence against invading microorganisms.
Acute inflammation is a form of innate immune defence and represents one of the primary …

Objective: To develop consensus statements for the diagnosis and management of
corticosteroid insufficiency in critically ill adult patients. Participants: A multidisciplinary …

Pneumonia and acute respiratory distress syndrome are common and important causes of
respiratory failure in the intensive care unit with a significant impact on morbidity, mortality …

Objective: Controversy remains as to whether low-dose corticosteroids can reduce the
mortality and morbidity of acute lung injury (ALI) or the acute respiratory distress syndrome …

Objective To systematically review the efficacy of steroids in the prevention of acute
respiratory distress syndrome (ARDS) in critically ill adults, and treatment for established …

Abstract Acute Respiratory Distress Syndrome (ARDS) is a common entity in critical care.
ARDS is associated with many diagnoses, including trauma and sepsis, can lead to multiple …

One of the most challenging problems in critical care medicine is the management of
patients with the acute respiratory distress syndrome. Increasing evidence from …

Experimental and clinical evidence has demonstrated a strong cause-and-effect relationship
between persistence vs reduction in systemic inflammation and progression (unresolving) vs …

The diagnosis of adrenal failure and the indications for corticosteroid therapy in critically ill
patients are controversial. This controversy is fueled by the complexity of the issues and the …