Memories of past events can be recalled long after the event, indicating stability. But new
experiences are also integrated into existing memories, indicating plasticity. In the …

Adult-born granule cells (abGCs) have been implicated in memory discrimination through a
neural computation known as pattern separation. Here, using in vivo Ca 2+ imaging, we …

The representation of distinct spaces by hippocampal place cells has been linked to
changes in their place fields (the locations in the environment where the place cells …

The quest to understand the memory engram has intrigued humans for centuries. Recent
technological advances, including genetic labeling, imaging, optogenetic and chemogenetic …

Episodic memories are encoded by experience-activated neuronal ensembles that remain
necessary and sufficient for recall. However, the temporal evolution of memory engrams …

Recent studies show that, even in constant environments, the tuning of single neurons
changes over time in a variety of brain regions. This representational drift has been …

Time and experience are independent determinants of representational drift in CA1 Page 1
Previews Time and experience are independent determinants of representational drift in …

Behavior can be remarkably consistent, even over extended time periods, yet whether this is
reflected in stable or 'drifting'neuronal responses to task features remains controversial …

Abstract Representation of the environment by hippocampal populations is known to drift
even within a familiar environment, which could reflect gradual changes in single cell activity …

Representational drift refers to the dynamic nature of neural representations in the brain
despite the behavior being seemingly stable. Although drift has been observed in many …