Gap junctions form channels between adjacent cells. The core proteins of these channels
are the connexins. Regulation of gap junction communication (GJC) can be modulated by …

The eye lens is constantly subjected to oxidative stress from radiation and other sources.
The lens has several mechanisms to protect its components from oxidative stress and to …

The cells of most mammalian organs are connected by groups of cell-to-cell channels called
gap junctions. Gap junction channels are made from the connexin (Cx) family of proteins …

The optical properties of the ocular lens are important to overall vision quality. As a
transparent biological tissue, the lens contributes to the overall and dynamic focussing …

The lens is the largest organ in the body that lacks a vasculature. The reason is simple:
blood vessels scatter and absorb light while the physiological role of the lens is to be …

Millions of people worldwide are blinded due to cataract formation. At present the only
means of treating a cataract is through surgical intervention. A modern cataract operation …

The purpose of this paper is to provide a brief overview of current thinking on the role of
connexins, in particular Cx43, in growth regulation, and a more detailed discussion as to …

Local injury induces a complex orchestrated response to stimulate healing of injured tissues,
cellular regeneration and phagocytosis. Practically, inflammation is defined as a defense …

Bone morphogenetic proteins (BMPs) are a diverse class of growth factors that belong to the
transforming growth factor-beta (TGFβ) superfamily. Although originally discovered to …

AKT pathway has a critical role in mediating signaling transductions for cell proliferation,
differentiation and survival. Previous studies have shown that AKT activation is achieved …