Parkinson's disease is thought to be caused by some unknown endogenous or exogenous
factors interacting with genetic dispositions. 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine …

Clinical interest in the levels of catechols in body fluids derives from fundamental issues
about the physiology of adaptive responses to stress: assessments of disease severity and …

This review evaluates the presumed contribution of acetaldehyde to tobacco smoke
addiction. In rodents, acetaldehyde induces reinforcing effects, and acts in concert with …

Discussions concerning normal endogenous metabolites of catecholamines and
indoleamines generally are restricted to deaminated, 0-methylated and/or conjugated …

Abstract Salsolinol (1-methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline) is a
tetrahydroisoquinoline derivative whose presence in humans was first detected in the urine …

Current diagnostic options for Parkinson's disease are very limited and primarily based on
characteristic clinical symptoms. Thus, there are urgent needs for reliable biomarkers that …

Background: Salsolinol, a condensation product of dopamine with acetaldehyde (the initial
oxidation product of ethanol), has long been discussed as an endogenous opioid system …

Tetrahydroisoquinolines and fJ-carbolines: putative natural substances in plants and
mammals * Page 1 I 2 2.1 2.2 2.3 3 3.1 3.11 3.111 3.112 3.113 3.12 3.2 3.3 3.4 3.41 3.411 …

The possible involvement of salsolinol (Sal), an endogenous condensation product of ACD
(the first metabolite of ethanol) and dopamine, in the neurochemical basis underlying …

Alcoholism is one of the most frequent addictions and an important subject in forensic
medicine and clinical toxicology. Several laboratory abnormalities are associated with …