Targeting strategies for bone diseases: signaling pathways and clinical studies
H Xu, W Wang, X Liu, W Huang, C Zhu, Y Xu… - … and Targeted Therapy, 2023 - nature.com
Since the proposal of Paul Ehrlich's magic bullet concept over 100 years ago, tremendous
advances have occurred in targeted therapy. From the initial selective antibody, antitoxin to …
advances have occurred in targeted therapy. From the initial selective antibody, antitoxin to …
[HTML][HTML] Recent developments in nanomaterials for upgrading treatment of orthopedics diseases
J Shang, C Zhou, C Jiang, X Huang, Z Liu… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Nanotechnology has changed science in the last three decades. Recent applications of
nanotechnology in the disciplines of medicine and biology have enhanced medical …
nanotechnology in the disciplines of medicine and biology have enhanced medical …
[HTML][HTML] Development of tetracycline-modified nanoparticles for bone-targeted delivery of anti-tubercular drug
Q Liang, P Zhang, L Zhang, H Luan, X Li… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Background: Since the poor response to existing anti-tuberculosis drugs and low drug
concentration in local bone tissues, the traditional drug therapy does not result in satisfactory …
concentration in local bone tissues, the traditional drug therapy does not result in satisfactory …
mRNA nanodelivery systems: targeting strategies and administration routes
M Yuan, Z Han, Y Liang, Y Sun, B He… - Biomaterials …, 2023 - spj.science.org
With the great success of coronavirus disease (COVID-19) messenger ribonucleic acid
(mRNA) vaccines, mRNA therapeutics have gained significant momentum for the prevention …
(mRNA) vaccines, mRNA therapeutics have gained significant momentum for the prevention …
Nanoparticle-Based Drug Delivery Systems for Enhancing Bone Regeneration
H Xu, Y Cui, Y Tian, M Dou, S Sun… - … Science & Engineering, 2024 - ACS Publications
The treatment of bone defects has been a long-standing challenge in clinical practice.
Among the various bone tissue engineering approaches, there has been substantial …
Among the various bone tissue engineering approaches, there has been substantial …
Bone Targeting Nanoparticles for the Treatment of Osteoporosis
C Wen, X Xu, Y Zhang, J Xia, Y Liang… - International Journal of …, 2024 - Taylor & Francis
Osteoporosis (OP) affects millions of people worldwide, especially postmenopausal women
and the elderly. Although current available anti-OP agents can show promise in slowing …
and the elderly. Although current available anti-OP agents can show promise in slowing …
Integrating osteoimmunology and nanoparticle-based drug delivery systems for enhanced fracture healing
Fracture healing is a complex interplay of molecular and cellular mechanisms lasting from
days to weeks. The inflammatory phase is the first stage of fracture healing and is critical in …
days to weeks. The inflammatory phase is the first stage of fracture healing and is critical in …
An update on the advances in the field of nanostructured drug delivery systems for a variety of orthopedic applications
W Liang, C Zhou, S Jin, L Fu, H Zhang, X Huang… - Drug Delivery, 2023 - Taylor & Francis
Nanotechnology has made significant progress in various fields, including medicine, in
recent times. The application of nanotechnology in drug delivery has sparked a lot of …
recent times. The application of nanotechnology in drug delivery has sparked a lot of …
Harnessing the Potential of PLGA Nanoparticles for Enhanced Bone Regeneration
Recently, nanotechnologies have become increasingly prominent in the field of bone tissue
engineering (BTE), offering substantial potential to advance the field forward. These …
engineering (BTE), offering substantial potential to advance the field forward. These …
[HTML][HTML] Citric acid-modified pH-sensitive bone-targeted delivery of estrogen for the treatment of postmenopausal osteoporosis
ZH Chen, DY Du, YF Fu, JJ Wu, DY Guo, YY Li… - Materials Today Bio, 2023 - Elsevier
Bone targeted delivery of estrogen offers great promise for the clinical application of
estrogen in the treatment of postmenopausal osteoporosis (PMOP). However, the current …
estrogen in the treatment of postmenopausal osteoporosis (PMOP). However, the current …