Nanomedicine approaches for advanced diagnosis and treatment of atherosclerosis and related ischemic diseases

B Hu, KO Boakye‐Yiadom, W Yu… - Advanced …, 2020 - Wiley Online Library
Cardiovascular diseases (CVDs) remain one of the major causes of mortality worldwide. In
response to this and other worldwide health epidemics, nanomedicine has emerged as a …

Atherosclerosis Treatment with Stimuli‐Responsive Nanoagents: Recent Advances and Future Perspectives

A Maruf, Y Wang, T Yin, J Huang… - Advanced …, 2019 - Wiley Online Library
Atherosclerosis is the root of approximately one‐third of global mortalities. Nanotechnology
exhibits splendid prospects to combat atherosclerosis at the molecular level by engineering …

Emerging cellular functions of the lipid metabolizing enzyme 15‐Lipoxygenase‐1

M Çolakoğlu, S Tunçer, S Banerjee - Cell proliferation, 2018 - Wiley Online Library
The oxygenation of polyunsaturated fatty acids such as arachidonic and linoleic acid
through lipoxygenases (LOX s) and cyclooxygenases (COX s) leads to the production of …

Ox-LDL causes endothelial cell injury through ASK1/NLRP3-mediated inflammasome activation via endoplasmic reticulum stress

L Hang, Y Peng, R Xiang, X Li, Z Li - Drug Design, Development …, 2020 - Taylor & Francis
Objective This study was to investigate the mechanism of inflammatory pathology
modification induced by ox-LDL in endothelial cells. Methodology In this study, we firstly …

Retinol-binding protein-dependent cholesterol uptake regulates macrophage foam cell formation and promotes atherosclerosis

Y Liu, Y Zhong, H Chen, D Wang, M Wang, JS Ou… - Circulation, 2017 - Am Heart Assoc
Background: Retinol-binding protein 4 (RBP4) is an adipokine that plays decisive roles in
glucose metabolism and insulin sensitivity. Elevated circulating RBP4 levels were reported …

Anti-inflammatory activity of the Tongmai Yangxin pill in the treatment of coronary heart disease is associated with estrogen receptor and NF-κB signaling pathway

Y Fan, J Liu, J Miao, X Zhang, Y Yan, L Bai… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance The Tongmai Yangxin Pill (TMYX) is a patented
traditional Chinese medicine originating from two classic prescriptions, Zhigancao …

Long noncoding RNAs and atherosclerosis

T Zhou, J Ding, XA Wang, X Zheng - Atherosclerosis, 2016 - Elsevier
Atherosclerosis is universally recognized as a chronic lipid-induced inflammation of the
vessel wall in response to dyslipidemia and haemodynamic stress involving dysfunction and …

Short-chain fatty acids are potential goalkeepers of atherosclerosis

Y Feng, D Xu - Frontiers in pharmacology, 2023 - frontiersin.org
Short-chain fatty acids (SCFAs) are metabolites produced by gut bacteria and play a crucial
role in various inflammatory diseases. Increasing evidence suggests that SCFAs can …

Spices and atherosclerosis

PF Tsui, CS Lin, LJ Ho, JH Lai - Nutrients, 2018 - mdpi.com
Cardiovascular disease is one of the leading causes of death and disability in the world.
Atherosclerosis, characterized by lipid accumulation and chronic inflammation in the vessel …

Eating the dead to keep atherosclerosis at bay

ML Brophy, Y Dong, H Wu, HNA Rahman… - Frontiers in …, 2017 - frontiersin.org
Atherosclerosis is the primary cause of coronary heart disease (CHD), ischemic stroke, and
peripheral arterial disease. Despite effective lipid-lowering therapies and prevention …