All patients with asthma are at risk of having exacerbations. Hospitalizations and emergency
department (ED) visits account for a large proportion of the health-care cost burden of …

Background Systemic corticosteroid therapy is central to the management of acute asthma.
The use of inhaled corticosteroids (ICS) may also be beneficial in this setting. Objectives To …

Background Randomized trials without reported adequate allocation concealment have
been shown to overestimate the benefit of experimental interventions. We investigated the …

Objective. To review the use of systemic corticosteroids to treat recurrent, acute asthma
episodes in children, with a focus on the role of oral corticosteroids. Methods. A …

Rationale: Several studies published in the second half of the 1990s have shown a
therapeutic early effect of inhaled corticosteroids in acute asthma. However, systemic …

BACKGROUND. Inhaled corticosteroids are not as effective as oral corticosteroids in school-
aged children with severe acute asthma. It is uncertain how inhaled corticosteroids compare …

Effective and efficient treatment of acute asthma in the emergency department requires
prompt recognition of the signs and symptoms that indicate a potentially fatal asthma attack …

Study objective This study tests the hypothesis that the administration of multiple doses of
inhaled albuterol (A), ipratropium bromide (IB), and flunisolide (F) provides an additional …

OBJECTIVE: To review the efficacy and safety of inhaled corticosteroids (ICSs) when used to
reduce daily oral corticosteroid (OCS) requirements in patients with severe persistent …

Asthma is a heterogeneous disease more appropriately seen as a syndrome rather than a
single pathologic entity. Although it can remain quiescent for extended time periods, the …