Chronic pain is long-lasting pain that often persists during chronic diseases or after recovery
from disease or injury. It often causes serious side effects, such as insomnia, anxiety, or …

Nociceptive signaling responses to painful stimuli are transmitted to the central nervous
system (CNS) from the afferent nerves of the periphery through a series of neurotransmitters …

Psychedelic mushrooms containing psilocybin and related tryptamines have long been used
for ethnomycological purposes, but emerging evidence points to the potential therapeutic …

Pain, the primary symptom of osteoarthritis (OA), reduces both the quality and quantity of life
for patients. The pathophysiology of OA pain is complex and often difficult to explain solely …

The physiopathology and neurotransmission of pain are of an owe inspiring complexity. Our
ability to satisfactorily suppress neuropathic or other forms of chronic pain is limited. The …

Simple Summary Fiber pathways that descend from the brain to the spinal cord drive motor
behavior and modulate incoming sensory signals and the capacity to change (plasticity). A …

Chronic neuropathic pain (CNP) refers to pain that lasts for more than three months due to a
disease or an injury to the somatosensory nervous system. The incidence of CNP has been …

Abstract The serotonergic (5‐HT) system, which undergoes degeneration in Parkinson's
disease (PD), is involved in the pathogenesis of motor and nonmotor symptoms. The dorsal …

Increasing evidence shows that gut microbiota is important for host health in response to
metal nanomaterials exposure. However, the effect of gut microbiota on the cortex damage …

The chances of people suffering from cognitive impairments increase gradually with age.
Diet and lifestyle are closely related to the occurrence and development of cognitive …