Discovered more than 30 years ago, the angiotensin AT2 receptor (AT2R) has evolved from
a binding site with unknown function to a firmly established major effector within the …

Molecular variants of individual components of the renin–angiotensin system (RAS) have
been thought to contribute to an inherited predisposition towards essential hypertension …

The angiotensin II type 1 receptor (AGTR1) plays an integral role in blood pressure control,
and is implicated in the pathogenesis of hypertension. Polymorphisms within this gene have …

Molecular variants of individual components of the renin-angiotensin system (RAS) are
thought to contribute to inherited predisposition towards essential hypertension. Poly …

Blood pressure (BP) response to infused angiotensin II (Ang II) has been widely used to
characterize hypertensive subjects. High cholesterol levels hav recently been found to …

In experimental studies, the importance of aldosterone for the development of left ventricular
(LV) hypertrophy has been demonstrated. In 120 healthy Caucasian men (aged 25±3 years; …

Background. The haemodynamic responses to angiotensin II type 1 (AT1) receptor blockade
may be mediated in part by interactions between angiotensin II and the angiotensin II type 2 …

Background The angiotensin II type 1 receptor (AT1R) 1166A/C polymorphism is reported to
be implicated in cardiovascular diseases. The association between the 1166A/C …

Essential hypertension (EH) is a polygenic and multifactorial disorder that results from
genetic and/or environmental factors (Lifton et al., 2001). This disease has no identifiable …

There are reported associations between a polymorphism of the angiotensin II type 1
receptor (AGTR. 1/A1166C) gene and hypertension in some populations. To study the …