MAFLD as part of systemic metabolic dysregulation
J Zhao, L Liu, YY Cao, X Gao, G Targher… - Hepatology …, 2024 - Springer
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases
worldwide. In recent years, a new terminology and definition of metabolic dysfunction …
worldwide. In recent years, a new terminology and definition of metabolic dysfunction …
The chronic consumption of dietary fructose promotes the gut Clostridium species imbalance and bile acid alterations in developing nonalcoholic fatty liver disease
D Zhang, H Wang, A Liu, S Wang, C Xu, K Lan… - The Journal of …, 2023 - Elsevier
Excessive fructose intake is associated with the rising prevalence of nonalcoholic fatty liver
disease (NAFLD). The gut microbiome (GM) and bile acids (BAs) are involved in the …
disease (NAFLD). The gut microbiome (GM) and bile acids (BAs) are involved in the …
[HTML][HTML] Vitamin C and vitamin D3 alleviate metabolic-associated fatty liver disease by regulating the gut microbiota and bile acid metabolism via the gut-liver axis
Q Chen, L Zhao, L Mei, X Zhao, P Han, J Liu… - Frontiers in …, 2023 - frontiersin.org
Background: Previous studies have demonstrated that both vitamin C (VC) and vitamin D 3
(VD 3) have therapeutic potential against metabolic disorders, including obesity, diabetes …
(VD 3) have therapeutic potential against metabolic disorders, including obesity, diabetes …
[HTML][HTML] Principles of risk stratification in nonalcoholic fatty liver disease. A narrative review emphasizing non-invasive strategies
A Lonardo - Exploration of Digestive Diseases, 2023 - explorationpub.com
Nonalcoholic fatty liver disease (NAFLD) is an umbrella definition that describes the ectopic
deposition of fat within the liver that occurs in the absence of inciting factors other than the …
deposition of fat within the liver that occurs in the absence of inciting factors other than the …
Bile acid alterations characterize the early onset and progression of nonalcoholic fatty liver disease in young mice fed with high fat and fructose diet
W Xiang, A Liu, C Xu, D Zhang, W Li… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope Bile acids (BAs) are closely associated with obesity and non‐alcoholic fatty liver
disease (NAFLD). How BAs change within the enterohepatic circulation during the onset …
disease (NAFLD). How BAs change within the enterohepatic circulation during the onset …
[HTML][HTML] Prediagnostic plasma metabolite concentrations and liver cancer risk: a population-based study of Chinese men
ZY Li, QM Shen, J Wang, JY Tuo, YT Tan, HL Li… - Ebiomedicine, 2024 - thelancet.com
Background Previous metabolic profiling of liver cancer has mostly used untargeted
metabolomic approaches and was unable to quantitate the absolute concentrations of …
metabolomic approaches and was unable to quantitate the absolute concentrations of …
Bile acids metabolism in the gut-liver axis mediates liver injury during lactation
L Huang, Y Li, R Tang, P Yang, Y Zhuo, X Jiang, L Che… - Life Sciences, 2024 - Elsevier
Aims The obesity epidemic, especially in pregnant women, linked to a higher risk of liver
diseases. Bile acids (BAs) are known to participate in liver metabolism, but this function …
diseases. Bile acids (BAs) are known to participate in liver metabolism, but this function …
Gut microbiota and metabolite interface-mediated hepatic inflammation
M Yang, K Massad, ET Kimchi… - …, 2024 - journals.lww.com
Immunologic and metabolic signals regulated by gut microbiota and relevant metabolites
mediate bidirectional interaction between the gut and liver. Gut microbiota dysbiosis, due to …
mediate bidirectional interaction between the gut and liver. Gut microbiota dysbiosis, due to …
Unravelling the therapeutic landscape of bile acid-based therapies in gastrointestinal disorders
BD Alrehaili - Saudi Journal of Gastroenterology, 2024 - journals.lww.com
Bile acids serve as endogenous ligands for nuclear and cell membrane receptors and play a
crucial role in bile acid and lipid metabolism. These detergent-like compounds promote bile …
crucial role in bile acid and lipid metabolism. These detergent-like compounds promote bile …
Dysregulated bile acid homeostasis: unveiling its role in metabolic diseases
Y Wang, H Xu, X Zhou, W Chen, H Zhou - Medical Review, 2024 - degruyter.com
Maintaining bile acid homeostasis is essential for metabolic health. Bile acid homeostasis
encompasses a complex interplay between biosynthesis, conjugation, secretion, and …
encompasses a complex interplay between biosynthesis, conjugation, secretion, and …