Are mast cells instrumental for fibrotic diseases?
C Overed-Sayer, L Rapley, T Mustelin… - Frontiers in …, 2014 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a fatal lung disorder of unknown etiology characterized
by accumulation of lung fibroblasts and extracellular matrix deposition, ultimately leading to …
by accumulation of lung fibroblasts and extracellular matrix deposition, ultimately leading to …
Mast cells: a pivotal role in pulmonary fibrosis
A Veerappan, NJ O'Connor, J Brazin, AC Reid… - DNA and cell …, 2013 - liebertpub.com
Pulmonary fibrosis is characterized by an inflammatory response that includes
macrophages, neutrophils, lymphocytes, and mast cells. The purpose of this study was to …
macrophages, neutrophils, lymphocytes, and mast cells. The purpose of this study was to …
NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFβ1-induced fibroblast …
N Amara, D Goven, F Prost, R Muloway, B Crestani… - Thorax, 2010 - thorax.bmj.com
Background Persistence of myofibroblasts is believed to contribute to the development of
fibrosis in idiopathic pulmonary fibrosis (IPF). Transforming growth factor β1 (TGFβ1) …
fibrosis in idiopathic pulmonary fibrosis (IPF). Transforming growth factor β1 (TGFβ1) …
Idiopathic pulmonary fibrosis and diffuse parenchymal lung disease: implications from initial experience with 18F-FDG PET/CT
The purpose of this study was to evaluate integrated 18F-FDG PET/CT in patients with
idiopathic pulmonary fibrosis (IPF) and diffuse parenchymal lung disease (DPLD). Methods …
idiopathic pulmonary fibrosis (IPF) and diffuse parenchymal lung disease (DPLD). Methods …
Plumbagin attenuates Bleomycin-induced lung fibrosis in mice
Background Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease with limited
treatment options. Plumbagin (PL) is an herbal extract with diverse pharmacological effects …
treatment options. Plumbagin (PL) is an herbal extract with diverse pharmacological effects …
Oxidative stress alters syndecan-1 distribution in lungs with pulmonary fibrosis
CR Kliment, JM Englert, BR Gochuico, G Yu… - Journal of Biological …, 2009 - ASBMB
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterized by severe,
progressive fibrosis. Roles for inflammation and oxidative stress have recently been …
progressive fibrosis. Roles for inflammation and oxidative stress have recently been …
Chitosan-alginate nano-carrier for transdermal delivery of pirfenidone in idiopathic pulmonary fibrosis
Pirfenidone (PFD) is one of the pyridine family components with anti-inflammatory,
antifibrotic effects and US FDA approved for the treatment of idiopathic pulmonary fibrosis …
antifibrotic effects and US FDA approved for the treatment of idiopathic pulmonary fibrosis …
Luteolin Ameliorates Experimental Lung Fibrosis Both in Vivo and in Vitro: Implications for Therapy of Lung Fibrosis
Lonicera japonica (Caprifoliaceae) has been known as an anti-inflammatory herb in
traditional Chinese medicine for thousands of years and is used constantly for upper …
traditional Chinese medicine for thousands of years and is used constantly for upper …
[HTML][HTML] Genomic phenotype of non-cultured pulmonary fibroblasts in idiopathic pulmonary fibrosis
MC Emblom-Callahan, MK Chhina, OA Shlobin… - Genomics, 2010 - Elsevier
Activated fibroblasts are the central effector cells of the progressive fibrotic process in
idiopathic pulmonary fibrosis (IPF). Characterizing the genomic phenotype of isolated …
idiopathic pulmonary fibrosis (IPF). Characterizing the genomic phenotype of isolated …
ATLa, an aspirin-triggered lipoxin A4 synthetic analog, prevents the inflammatory and fibrotic effects of bleomycin-induced pulmonary fibrosis
V Martins, SS Valenca, FA Farias-Filho… - The Journal of …, 2009 - journals.aai.org
Despite an increase in the knowledge of mechanisms and mediators involved in pulmonary
fibrosis, there are no successful therapeutics available. Lipoxins (LX) and their 15-epimers …
fibrosis, there are no successful therapeutics available. Lipoxins (LX) and their 15-epimers …