The urogenital tract is a complex environment composed of many different types of epithelial
tissues and innate immune cells that sample the surrounding milieu. As a host-adapted …

The solute binding proteins (SBPs) of prokaryotes are present in the extracytosolic space.
Although their primary function is providing substrates to transporters, SBPs also stimulate …

Neisseria gonorrhoeae, the causative agent of the sexually transmitted disease
gonorrhoeae, possesses several mobile genetic elements (MGEs). The MGEs such as …

Increasing antibiotic resistance of Neisseria gonorrhoeae, the causative agent of gonorrhea,
is a growing global concern that has renewed vaccine development efforts. The gonococcal …

Porphyromonas gingivalis, a keystone pathogen of chronic periodontitis, uses ferric uptake
regulator homolog (PgFur) to regulate production of virulence factors. This study aimed to …

Neisseria gonorrhoeae mounts a substantial transcriptional program in response to
hydrogen peroxide (HP), a prominent reactive oxygen species (ROS) encountered during …

Partitioning proteins are well studied as molecular organizers of chromosome and plasmid
segregation during division, however little is known about the roles partitioning proteins can …

ABSTRACT Neisseria gonorrhoeae (gonococcus [Ng]) is the causative organism of the
sexually transmitted disease gonorrhoea, and no effective vaccine exists currently. In this …

The arsenic acid-resistant (ArsR) family transcriptional regulators are widely distributed in
microorganisms, including in the facultative intracellular pathogen Brucella spp. ArsR …

Iron is required for key metabolic processes but is toxic in excess. This circumstance forces
organisms across the tree of life to tightly regulate iron homeostasis. In hypersaline lakes …