Plasma cells are unique immune effectors, capable of producing large amounts of high-
affinity antibodies that protect against pathogenic infections. Although most plasma cells …

Atherosclerosis (AS) is a chronic inflammatory disease caused by disorders of lipid
metabolism. Abnormal deposition of low-density lipoproteins in the arterial wall stimulates …

Infants and young children are more susceptible to common respiratory pathogens than
adults but can fare better against novel pathogens like severe acute respiratory syndrome …

While blood antibodies mediate protective immunity in most organs, whether they protect
nasal surfaces in the upper airway is unclear. Using multiple viral infection models in mice …

Allergen-specific immunoglobulin E (IgE) antibodies mediate pathology in diseases such as
allergic rhinitis and food allergy. Memory B cells (MBCs) contribute to circulating IgE by …

Memory B cells (MBCs) can persist for a lifetime, but the mechanisms that allow their long-
term survival remain poorly understood. Here, we isolated and analyzed human splenic …

Memory B cells (MBCs) are phenotypically and functionally diverse, but their developmental
origins remain undefined. Murine MBCs can be divided into subsets by expression of CD80 …

Acinetobacter baumannii is a leading cause of antibiotic-resistant nosocomial infections with
high mortality rates, yet there is currently no clinically approved vaccine formulation. During …

While vaccines have been highly successful in protecting against various infections, there
are still many high‐priority pathogens for which there are no clinically approved …

Adaptive immunity provides protection against infectious and malignant diseases. These
effects are mediated by lymphocytes that sense and respond with targeted precision to …