Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

The structure of connective tissues including cartilage, tendons, and ligaments as well as
many organs, like the skin, heart, liver, kidney, lungs, blood vessels, and bones, depend on …

Idiopathic pulmonary fibrosis (IPF) is an irreversible and fatal lung disease that is primarily
found in the elderly population, and several studies have demonstrated that aging is the …

Dysregulated cell-cell communication is a hallmark of many disease phenotypes. Due to
recent advances in single-cell transcriptomics and computational approaches, it is now …

Oral submucous fibrosis (OSF) is a potentially malignant disorder of the oral mucosa;
however, whether and how the fibrotic matrix of OSF is involved in the malignant …

This study aimed to assess the protective effect of an extract of Lonicera japonica against
particulate-matter (PM) 2.5-induced pulmonary inflammation and fibrosis. The compounds …

Fibrotic diseases, such as systemic sclerosis (SSc), idiopathic pulmonary fibrosis, renal
fibrosis and liver cirrhosis are characterized by tissue overgrowth due to excessive …

Fibro-adipogenic progenitors (FAPs) are key regulators of skeletal muscle regeneration and
homeostasis. However, dysregulation of these cells leads to fibro-fatty infiltration across …

Idiopathic pulmonary fibrosis is a progressive and fatal disease with a poor prognosis. Matrix
metalloproteinase-2 is involved in the pathogenesis of organ fibrosis. The role of matrix …

Pulmonary fibrosis (PF) is a progressive chronic lung disease characterized by excessive
deposition of extracellular matrix (ECM) and structural destruction, associated with a severe …