[HTML][HTML] Monoclonal antibody-based molecular imaging strategies and theranostic opportunities

N Dammes, D Peer - Theranostics, 2020 - ncbi.nlm.nih.gov
Molecular imaging modalities hold great potential as less invasive techniques for diagnosis
and management of various diseases. Molecular imaging combines imaging agents with …

C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients

S Tsimikas, JT Willerson, PM Ridker - Journal of the American College of …, 2006 - jacc.org
Several emerging plasma biomarkers may ultimately prove useful in risk stratification and
prognosis of cardiovascular disease. The clinical utility of these biomarkers will depend on …

Imaging the vulnerable plaque

D Vancraeynest, A Pasquet, V Roelants… - Journal of the American …, 2011 - jacc.org
Cardiovascular diseases are still the primary causes of mortality in the United States and in
Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and …

[HTML][HTML] Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events

S Tsimikas, ES Brilakis, RJ Lennon, ER Miller… - Journal of lipid …, 2007 - ASBMB
The relationship between autoantibodies to oxidized low density lipoprotein (OxLDL) and
coronary artery disease (CAD) remains controversial. IgM and IgG OxLDL autoantibodies to …

Oxidative stress and reactive oxygen species

F Galli, M Piroddi, C Annetti, C Aisa, E Floridi… - Cardiovascular …, 2005 - karger.com
This article discusses different aspects concerning classification/nomenclature, biochemical
properties and pathophysiological roles of 'reactive oxygen species'(ROS) which are pivotal …

Oxidative modification of lipoproteins: mechanisms, role in inflammation and potential clinical applications in cardiovascular disease

S Tsimikas, YI Miller - Current pharmaceutical design, 2011 - ingentaconnect.com
Abnormalities of lipid metabolism often lead to pathologic lipid accumulation in the vessel
wall, oxidative and chronic inflammatory sequelae and the formation of atherosclerotic …

[HTML][HTML] Differential expression of oxidation-specific epitopes and apolipoprotein (a) in progressing and ruptured human coronary and carotid atherosclerotic lesions

RA Van Dijk, F Kolodgie, A Ravandi, G Leibundgut… - Journal of lipid …, 2012 - ASBMB
The relationships between oxidation-specific epitopes (OSE) and lipoprotein (a)[Lp (a)] and
progressive atherosclerosis and plaque rupture have not been determined. Coronary artery …

Molecular and cellular imaging of atherosclerosis: emerging applications

FA Jaffer, P Libby, R Weissleder - Journal of the American College of …, 2006 - jacc.org
Molecular and Cellular Imaging of Atherosclerosis: Emerging Applications Farouc A. Jaffer,
Peter Libby, Ralph Weissleder Molecular imaging studies have shed light on important …

The vascular biology of atherosclerosis and imaging targets

P Libby, M DiCarli, R Weissleder - Journal of Nuclear Medicine, 2010 - Soc Nuclear Med
The growing worldwide health challenge of atherosclerosis, together with advances in
imaging technologies, have stimulated considerable interest in novel approaches to …

Targeted molecular probes for imaging atherosclerotic lesions with magnetic resonance using antibodies that recognize oxidation-specific epitopes

KC Briley-Saebo, PX Shaw, WJM Mulder, SH Choi… - Circulation, 2008 - Am Heart Assoc
Background—Oxidized low-density lipoprotein plays a key role in the initiation, progression,
and destabilization of atherosclerotic plaques and is present in macrophages and the lipid …