The endothelium plays a key role in blood vessel health. At the interface of the blood, it
releases several mediators that regulate local processes that protect against the …

The atheroprotective property of High Density Lipoprotein (HDL) is supported by many
epidemiological studies and cellular and in vivo approaches on animal models. While the …

Breathing is regulated by a host of arousal and sleep-wake state-dependent
neuromodulators to maintain respiratory homeostasis. Modulators such as acetylcholine …

The P2Y14 receptor (P2Y14R), one of eight P2Y G protein-coupled receptors (GPCR), is
involved in inflammatory, endocrine, and hypoxic processes and is an attractive …

Chronic inflammatory diseases and persistent pain of different origin represent common
medical, social, and economic burden, and their pharmacotherapy is still an unresolved …

Oxidative stress and the related inflammatory responses are closely associated with many
diseases including cardiovascular diseases such as atherosclerosis. Especially …

P2Y receptors are expressed in virtually all cells and tissue types and mediate an
astonishing array of biological functions, including platelet aggregation, smooth muscle cell …

Abstract Background/Aims: High-density lipoproteins (HDL) exert multiple cardioprotective
functions on the arterial wall, including the promotion of endothelial cell survival and …

Abstract The P2Y 14 R is a G i/o-coupled receptor of the P2Y family of purinergic receptors
that is activated by extracellular UDP and UDP-glucose (UDPG). In an earlier report we …

Adipose tissue contains self-renewing multipotent cells termed mesenchymal stromal cells.
In situ, these cells serve to expand adipose tissue by adipogenesis, but their multipotency …