Impaired Aβ clearance: a potential link between atherosclerosis and Alzheimer's disease

A Gupta, C Iadecola - Frontiers in aging neuroscience, 2015 - frontiersin.org
Alzheimer's Disease (AD) and atherosclerosis remain two of the largest public health
burdens in the world today. Although traditionally considered distinct pathological entities …

Targeted delivery of nano-therapeutics for major disorders of the central nervous system

H Gao, Z Pang, X Jiang - Pharmaceutical research, 2013 - Springer
Major central nervous system (CNS) disorders, including brain tumors, Alzheimer's disease,
Parkinson's disease, and stroke, are significant threats to human health. Although …

Data-efficient deep learning of radiological image data for outcome prediction after endovascular treatment of patients with acute ischemic stroke

A Hilbert, LA Ramos, HJA van Os… - Computers in biology …, 2019 - Elsevier
Abstract Treatment selection is becoming increasingly more important in acute ischemic
stroke patient care. Clinical variables and radiological image biomarkers (old age, pre …

Radiologically isolated syndrome or subclinical multiple sclerosis: MAGNIMS consensus recommendations

N De Stefano, A Giorgio, M Tintoré… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Nicola De Stefano, Antonio Giorgio, Mar Tintoré, Maria Pia Amato, Ludwig Kappos,
Jacqueline Palace, Tarek Yousry, Maria A Rocca, Olga Ciccarelli, Christian Enzinger, Jette …

[HTML][HTML] Functional MRI of brain physiology in aging and neurodegenerative diseases

JJ Chen - Neuroimage, 2019 - Elsevier
Brain aging and associated neurodegeneration constitute a major societal challenge as well
as one for the neuroimaging community. A full understanding of the physiological …

Claudin-1-targeted nanoparticles for delivery to aging-induced alterations in the blood–brain barrier

BA Bony, AW Tarudji, HA Miller, S Gowrikumar, S Roy… - Acs Nano, 2021 - ACS Publications
Aging-induced alterations to the blood–brain barrier (BBB) are increasingly being seen as a
primary event in chronic progressive neurological disorders that lead to cognitive decline …

[HTML][HTML] Motor imagery-based rehabilitation: potential neural correlates and clinical application for functional recovery of motor deficits after stroke

Y Tong, JT Pendy Jr, WA Li, H Du, T Zhang… - Aging and …, 2017 - ncbi.nlm.nih.gov
Motor imagery (MI), defined as the mental implementation of an action in the absence of
movement or muscle activation, is a rehabilitation technique that offers a means to replace …

Anatomical labeling of intracranial arteries with deep learning in patients with cerebrovascular disease

A Hilbert, J Rieger, VI Madai, EM Akay… - Frontiers in …, 2022 - frontiersin.org
Brain arteries are routinely imaged in the clinical setting by various modalities, eg, time-of-
flight magnetic resonance angiography (TOF-MRA). These imaging techniques have great …

[HTML][HTML] CLARITY for high-resolution imaging and quantification of vasculature in the whole mouse brain

LY Zhang, P Lin, J Pan, Y Ma, Z Wei, L Jiang… - Aging and …, 2018 - ncbi.nlm.nih.gov
Elucidating the normal structure and distribution of cerebral vascular system is fundamental
for understanding its function. However, studies on visualization and whole-brain …

[HTML][HTML] Invasion of peripheral immune cells into brain parenchyma after cardiac arrest and resuscitation

C Zhang, NR Brandon, K Koper, P Tang, Y Xu… - Aging and …, 2018 - ncbi.nlm.nih.gov
Although a direct link has long been suspected between systemic immune responses and
neuronal injuries after stroke, it is unclear which immune cells play an important role. A …