Tailoring supramolecular short peptide nanomaterials for antibacterial applications

M Abbas, M Ovais, A Atiq, TM Ansari, R Xing… - Coordination Chemistry …, 2022 - Elsevier
The rise of bacterial resistance to current antibiotics poses a threat to humanity and
reinforces the need for new-generation nanomaterials with antibacterial properties and …

Strategic approaches to improvise peptide drugs as next generation therapeutics

P Barman, S Joshi, S Sharma, S Preet… - International journal of …, 2023 - Springer
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

Curvature-sensing peptide inhibits tumour-derived exosomes for enhanced cancer immunotherapy

S Shin, H Ko, CH Kim, BK Yoon, S Son, JA Lee… - Nature Materials, 2023 - nature.com
Tumour-derived exosomes (T-EXOs) impede immune checkpoint blockade therapies,
motivating pharmacological efforts to inhibit them. Inspired by how antiviral curvature …

Role and modulation of the secondary structure of antimicrobial peptides to improve selectivity

Y Liang, X Zhang, Y Yuan, Y Bao, M Xiong - Biomaterials Science, 2020 - pubs.rsc.org
Since the development of bacterial resistance, the decreasing effectiveness of antibiotics is
becoming one of the most critical problems worldwide. Novel antibacterial agents are …

Application of the all-hydrocarbon stapling technique in the design of membrane-active peptides

HX Luong, HTP Bui, TT Tung - Journal of Medicinal Chemistry, 2022 - ACS Publications
The threats of drug resistance and new emerging pathogens have led to an urgent need to
develop alternative treatment therapies. Recently, considerable research efforts have …

Stopping membrane-enveloped viruses with nanotechnology strategies: Toward antiviral drug development and pandemic preparedness

BK Yoon, WY Jeon, TN Sut, NJ Cho, JA Jackman - ACS nano, 2020 - ACS Publications
Membrane-enveloped viruses are a leading cause of viral epidemics, and there is an
outstanding need to develop broad-spectrum antiviral strategies to treat and prevent …

Molecular fingerprinting of biological nanoparticles with a label-free optofluidic platform

A Stollmann, J Garcia-Guirado, JS Hong… - Nature …, 2024 - nature.com
Label-free detection of multiple analytes in a high-throughput fashion has been one of the
long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing …

Antimicrobial peptides and their applications in biomedical sector

A Sultana, H Luo, S Ramakrishna - Antibiotics, 2021 - mdpi.com
In a report by WHO (2014), it was stated that antimicrobial resistance is an arising challenge
that needs to be resolved. This resistance is a critical issue in terms of disease or infection …

Advances in antiviral material development

L Liang, A Ahamed, L Ge, X Fu, G Lisak - ChemPlusChem, 2020 - Wiley Online Library
The rise in human pandemics demands prudent approaches in antiviral material
development for disease prevention and treatment by effective protective equipment and …

The mechanism of membrane permeabilization by peptides: still an enigma

WC Wimley, K Hristova - Australian journal of chemistry, 2019 - CSIRO Publishing
Peptide-induced permeabilization of lipid vesicles has been measured for decades and has
provided many insights into the sequence–structure–function relationships of membrane …