Integrins are transmembrane receptors that have been implicated in the biology of various
human physiological and pathological processes. These molecules facilitate cell …

Age‐related macular degeneration (AMD) is a well‐characterized and extensively studied
disease. It is currently considered the leading cause of visual disability among patients over …

An effective host defense mechanism involves inflammation to eliminate pathogens from the
site of infection, followed by the resolution of inflammation and the restoration of tissue …

Integrins are cell adhesion receptors, which are typically transmembrane glycoproteins that
connect to the extracellular matrix (ECM). The function of integrins regulated by biochemical …

Glioma has been considered resistant to chemotherapy and radiation. Recently,
concomitant and adjuvant chemoradiotherapy with temozolomide has become the standard …

Anti‐angiogenesis is a promising strategy for the treatment of cancer. Integrins, consisting of
two noncovalently bound transmembrane α and β subunits, are an important molecular …

Integrin-associated signalling renders cells more resistant to genotoxic anti-cancer agents
like ionizing radiation and chemotherapeutic substances, a phenomenon termed cell …

The cross-talk between receptor tyrosine kinases and integrin receptors are known to be
crucial for a number of cellular functions. On endothelial cells, an interaction between …

The functional responses of endothelial cells are dependent on signaling from peptide
growth factors and the cellular adhesion receptors, integrins. These include cell adhesion …

The research of integrin-targeted anticancer agents has recorded important advancements
in ingenious design of delivery systems, based either on the prodrug approach, or on …