Alzheimer's disease (AD) is a frequent and disabling neurodegenerative disorder, in which
astrocytes participate in several pathophysiological processes including neuroinflammation …

Highlights•Drosophila glia share many properties with their mammalian
counterparts.•Different subpopulations of glia cells cooperate to support neuronal energy …

Obesity is a major risk factor of Alzheimer's disease and related dementias. The principal
feature of dementia is a loss of neurons and brain atrophy. The mechanistic links between …

Cell‐cell interactions in the central nervous system are based on the release of molecules
mediating signal exchange and providing structural and trophic support through vesicular …

Aging is intrinsically related to metabolic changes and characterized by the accumulation of
oxidative and inflammatory damage, as well as alterations in gene expression and activity of …

Astrocytes are key players in brain homeostasis and function. During the last years, several
studies have cemented this notion by showing that these cells respond to neuronal signals …

Alzheimer's disease (AD) is the most common form of dementia, resulting in disability and
mortality. The global incidence of AD is consistently surging. Although numerous therapeutic …

Astrocytes, the predominant glial cell type in the mammalian brain, influence a wide variety
of brain parameters including neuronal energy metabolism. Exciting recent studies have …

Abstract Glucose transporter-2 (GLUT2) monitors cellular glucose uptake. Astrocyte GLUT2
controls glucose counterregulatory hormone secretion. In vivo gene silencing and laser …

Metabolic disorders induced by arsenic exposure have attracted great public concern.
However, it remains unclear whether hypothalamus-based central regulation mechanisms …