Nanotheranostics, the integration of diagnostic and therapeutic function in one system using
the benefits of nanotechnology, is extremely attractive for personalized medicine. Because …

Targeted delivery of chemotherapeutics is defined in the sense, that is, to maximize the
therapeutic index of a chemotherapeutic agent by strictly localizing its pharmacological …

Coagulation abnormalities occur frequently in cancer patients. It is becoming evident that
blood platelets have an important function in this process. However, understanding of the …

Conspectus The development of sequence-specific peptidomimetics has led to a variety of
fascinating discoveries in chemical biology. Many peptidomimetics can mimic primary …

Vascular development requires correct interactions among endothelial cells, pericytes and
surrounding cells. These interactions involve many cell adhesion interactions, including cell …

CD23 is the low-affinity receptor for immunoglobulin (Ig) E and plays important roles in the
regulation of IgE responses. CD23 can be cleaved from cell surfaces to yield a range of …

We report the use of arginine-glycine-aspartic (Arg-Gly-Asp, RGD) peptide-modified
dendrimer-entrapped gold nanoparticles (Au DENPs) for highly efficient and specific gene …

The integrin αvβ3 plays an important role in angiogenesis and tumor metastasis. It is
expressed on activated endothelial cells as well as some tumor cells. Therefore it is a …

Nanohybrids based on biomolecular nanostructures and graphene quantum dots (GQDs)
have found wide application in the biological and biomedical fields. Herein, the design of a …

Inhibitors targeting the integrin αvβ3 are promising new agents currently tested in clinical
trials for supplemental therapy of glioblastoma multiforme (GBM). The aim of our study was …