Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis

KA Staats, DR Borchelt, MG Tansey… - Molecular …, 2022 - Springer
Abstract Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease in
which many processes are detected including (neuro) inflammation. Many drugs have been …

Overview of stem cells therapy in amyotrophic lateral sclerosis

G Je, K Keyhanian, M Ghasemi - Neurological Research, 2021 - Taylor & Francis
Background: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative
disease of upper and lower motor neurons with high burden on society. Despite tremendous …

Long‐Term Effects of Adjuvant Intravitreal Treatment with Autologous Bone Marrow‐Derived Lineage‐Negative Cells in Retinitis Pigmentosa

MP Wiącek, W Gosławski, A Grabowicz… - Stem Cells …, 2021 - Wiley Online Library
Background. Autologous bone marrow‐derived lineage‐negative (Lin−) cells present
antiapoptotic and neuroprotective activity. The aim of the study was to evaluate the safety …

Transplantation of Human Glial Progenitors to Immunodeficient Neonatal Mice with Amyotrophic Lateral Sclerosis (SOD1/rag2)

L Stanaszek, P Rogujski, K Drela, M Fiedorowicz… - Antioxidants, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a progressive, fatal disease with no effective therapy.
The neurodegenerative character of ALS was an appealing target for stem cell-based …

Humoral Influence of Repeated Lineage‐Negative Stem/Progenitor Cell Administration on Articulatory Functions in ALS Patients

A Sobuś, B Baumert, W Pawlukowska… - Stem Cells …, 2020 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) remains a fatal, neurodegenerative disease frequently
leading to dysarthria and impaired swallowing. Better understanding of ALS …

Spinal Cellular Implants in Treatment of Neurodegenerative Disorders

Y Kobayashi, JD Ciacci, M Marsala - Neuraxial Therapeutics: A …, 2024 - Springer
Several spinal pathological conditions may lead to an abrupt or progressive degeneration of
spinal gial cells and/or neurons and resulting loss of neurological function. Once a critical …

Adjuvant Lineage-Negative Cell Therapy as a Potential Silencer of the Complement-Mediated Immune System in ALS Patients

A Sobuś, B Baumert, M Gołąb-Janowska… - Journal of Clinical …, 2021 - mdpi.com
ALS remains a fatal, neurodegenerative motor neuron disease. Numerous studies seem to
confirm that innate immune system is involved in the pathophysiology of ALS. Hence, the …

Deciphering the Code: Stem Cell-Immune Function and Cardiac Regeneration

G Steinhoff - Cells, 2021 - mdpi.com
The development of stem-cell-based and regenerative therapies for cardiovascular and
other diseases has faced an unexpected roadblock in clinical translation [1]. Emerging …

Deciphering the Code: Stem Cell-Immune Function and Cardiac Regeneration. Cells 2021, 10, 592

G Steinhoff - 2021 - search.proquest.com
Emerging knowledge from clinical research points in the direction of bone marrow stem
cell/immune progenitor cell senescence by epigenetic and somatic mutations being the …

[PDF][PDF] Rogi nska

A Sobus, B Baumert, M Gołab-Janowska, P Kulig… - J. Clin. Med, 2021 - academia.edu
ALS remains a fatal, neurodegenerative motor neuron disease. Numerous studies seem to
confirm that innate immune system is involved in the pathophysiology of ALS. Hence, the …