Developing phytoestrogens for breast cancer prevention

MM Liu, Y Huang, J Wang - Anti-Cancer Agents in Medicinal …, 2012 - ingentaconnect.com
Breast cancer is one of the most common types of cancer in women, and is the second
leading cause of cancer-related deaths in the United States. Chemoprevention using …

Ferulic acid combined with aspirin demonstrates chemopreventive potential towards pancreatic cancer when delivered using chitosan-coated solid-lipid nanoparticles

A Thakkar, S Chenreddy, J Wang, S Prabhu - Cell & Bioscience, 2015 - Springer
Background The overall goal of this study was to demonstrate potential chemopreventive
effects of ferulic acid (FA), an antioxidant, combined with aspirin (ASP), a commonly used …

Polyphenolic coumpounds in Chemoprevention of colon cancer-Targets and signaling pathways

E Rudolf, H Andelova… - Anti-Cancer Agents in …, 2007 - ingentaconnect.com
Colorectal cancer is one of the leading causes of premature death in people worldwide. Due
to the fact that malignant conversion of normal colonic cells requires several steps and often …

Inhibition Of Tumorigenesis in ApcMin/+ Mice by a Combination of (–)-Epigallocatechin-3-gallate and Fish Oil

M Bose, X Hao, J Ju, A Husain, S Park… - J. of Agricultural and …, 2007 - ACS Publications
The effect of a combination of (–)-epigallocatechin-3-gallate (EGCG) with fish oil on
intestinal tumorigenesis in Apc Min/+ mice fed a high-fat diet was investigated in the present …

[HTML][HTML] Novel nano-drug combination therapeutic regimen demonstrates significant efficacy in the transgenic mouse model of pancreatic ductal adenocarcinoma

A Thakkar, P Desai, S Chenreddy, J Modi… - American journal of …, 2018 - ncbi.nlm.nih.gov
The current work studied the chemopreventive efficacy of orally administered chitosan
coated solid-lipid nanoparticle (c-SLN) encapsulated aspirin (ASP), curcumin (CUR) and …

Development and validation of a high‐performance liquid chromatography method for the simultaneous determination of aspirin and folic acid from nano‐particulate …

A Chaudhary, J Wang, S Prabhu - Biomedical Chromatography, 2010 - Wiley Online Library
Attention has shifted from the treatment of colorectal cancer (CRC) to chemoprevention
using aspirin and folic acid as agents capable of preventing the onset of colon cancer …

[HTML][HTML] Upregulation of the growth arrest-specific-2 in recurrent colorectal cancers, and its susceptibility to chemotherapy in a model cell system

CJ Huang, CL Lee, SH Yang, CC Chien… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Colorectal cancer (CRC) is one of the most common life-threatening malignances
worldwide. CRC relapse markedly decreases the 5-year survival of patients following …

Nanoparticulate delivery of novel drug combination regimens for the chemoprevention of colon cancer

N Kanthamneni, A Chaudhary… - … journal of oncology, 2010 - spandidos-publications.com
The purpose of this work was to assess synergistic inhibitory responses of a novel
chemopreventive combination regimen of drugs namely, aspirin in combination with calcium …

Chemoprevention of colon carcinogenesis by polyethylene glycol: suppression of epithelial proliferation via modulation of SNAIL/β-catenin signaling

HK Roy, DP Kunte, JL Koetsier, J Hart, YL Kim… - Molecular cancer …, 2006 - AACR
Polyethylene glycol (PEG) is one of the most potent chemopreventive agents against
colorectal cancer; however, the mechanisms remain largely unexplored. In this study, we …

Cyclin D1 A870G polymorphism and the risk of colorectal cancer and adenoma

ES Schernhammer, GJ Tranah, E Giovannucci… - British journal of …, 2006 - nature.com
Abstract Cyclin D1 (CCND1) plays a key role in cell cycle control, particularly in the transition
from G 1 to S phase, which is regulated by cyclin-dependent kinases. A common adenine to …