Aim To perform a systematic review and meta‐analysis on the efficacy and tolerance of
infliximab in ulcerative colitis. Methods Selection of studies: evaluating efficacy of infliximab …

Simple epithelial keratins K8 and K18 are components of the intracellular cytoskeleton in the
cells of the single‐layered sheet tissues inside the body. As members of the intermediate …

The cause of Crohn's disease (CD) remains poorly understood. Counterintuitively, these
patients possess an impaired acute inflammatory response, which could result in delayed …

BACKGROUND & AIMS:: We investigated if inhibition of mitogen-activated protein kinases
(MAPKs) was beneficial in Crohn's disease. METHODS:: Inhibition of JNK and p38 MAPK …

BACKGROUND & AIMS: Anti–tumor necrosis factor (TNF) α antibodies are effective in
treating patients with Crohn's disease whereas soluble TNFα receptors have not shown …

Necrosis of skeletal muscle fibers in the lethal childhood myopathy Duchenne muscular
dystrophy (DMD) results from defects in the cell membrane‐associated protein dystrophin …

Background: Two-thirds to three-fourths of patients with either refractory luminal or fistulizing
Crohn disease respond to infliximab treatment. The ability or inability to respond seems to …

OBJECTIVES: The aim of this study was to assess the efficacy and safety of a single infusion
of infliximab in the treatment of pediatric Crohn's disease (CD). METHODS: A total of 21 …

Background: The human anti-tumour necrosis factor (TNF) antibody infliximab binds to the
membrane TNF and subsequently induces apoptosis of activated lamina propria T …

Objective and design: This study aimed to determine if mucosal expression of the
chemokines IL-8, RANTES and MCP-1 and the pro-inflammatory cytokines TNFα and IL-6 …