Although the great effectiveness of doxorubicin (Dox) in the treatment of many types of
tumors, it showed limited effectiveness against the head and neck squamous cell carcinoma …

In this article, we continued our previous effort to develop new selective anticancer
candidates based on the basic pharmacophoric requirements of both EGFR and VEGFR-2 …

Cadmium (Cd) is a toxic heavy metal that is known to accumulate in various organs and
tissues in the body, including the testes. Exposure to Cd has been shown to cause …

A novel series of ethylidenehydrazineylthiazol-4 (5H)-ones were synthesized using various
eco-friendly one-pot multicomponent synthetic techniques. The anticancer activity of …

Human health is experiencing several obstacles in the modern medical era, particularly
cancer. As a result, the cancer therapeutic arsenal should be continually expanded with …

An immune system response known as inflammation can be carried on by a variety of things,
such as infections, damaged cells, and noxious substances. These factors may cause acute …

Abstract New 5‐cyano‐6‐oxo‐pyridine‐based sulfonamides (6a–m and 8a–d) were
designed and synthesized to potentially inhibit both the epidermal growth factor receptor …

Aim: Our objective was to design and synthesize a new range of pyrazolopyrimidines while
maintaining the key pharmacophoric features of EGFR tyrosine kinase inhibitors. Materials & …

Acinetobacter baumannii (A. baumannii) is an important pathogen that causes hospital-
acquired illnesses worldwide. The biofilm-forming activity of the organism enhances its …

The ongoing research in cancer treatment underscores the significance of dual epidermal
growth factor receptor (EGFR) kinase inhibitors targeting both mutant and wild-type variants …