Review on crosstalk and common mechanisms of endocrine disruptors: Scaffolding to improve PBPK/PD model of EDC mixture

RP Sharma, M Schuhmacher, V Kumar - Environment international, 2017 - Elsevier
Endocrine disruptor compounds (EDCs) are environment chemicals that cause harmful
effects through multiple mechanisms, interfering with hormone system resulting in alteration …

Endocrine disrupting chemicals and metabolic disorders in the liver: What if we also looked at the female side?

B Le Magueresse-Battistoni - Chemosphere, 2021 - Elsevier
Endocrine disrupting chemicals (EDCs) are linked to the worldwide epidemic incidence of
metabolic disorders and fatty liver diseases, which affects quality of life and represents a …

Angiogenesis signaling in breast cancer models is induced by hexachlorobenzene and chlorpyrifos, pesticide ligands of the aryl hydrocarbon receptor

LV Zárate, CA Pontillo, A Español, NV Miret… - Toxicology and Applied …, 2020 - Elsevier
Breast cancer incidence is increasing globally and pesticides exposure may impact risk of
developing this disease. Hexachlorobenzene (HCB) and chlorpyrifos (CPF) act as …

[HTML][HTML] Clarity in the face of confusion: new studies tip the scales on bisphenol A (BPA)

LN Vandenberg, GS Prins - Andrology, 2016 - ncbi.nlm.nih.gov
By now, bisphenol A (BPA) has become a 'household name'; many consumers are aware of
this compound and the various products where it is found. BPA is used in a wide range of …

[HTML][HTML] Novel, highly sensitive, in vivo screening method detects estrogenic activity at low doses of bisphenol A

K Ishida, M Furukawa, M Kunitani, R Yamagiwa… - Journal of Hazardous …, 2023 - Elsevier
Low doses of bisphenol A (BPA), a typical endocrine-disrupting chemical (EDC), have been
reported to exhibit estrogenic action in animals; however, the effects have not been fully …

Mixture toxicity, cumulative risk, and environmental justice in United States federal policy, 1980–2016: Why, with much known, was little done?

RH Sprinkle, DC Payne-Sturges - Environmental Health, 2021 - Springer
Abstract Toxic chemicals—“toxicants”—have been studied and regulated as single entities,
and, carcinogens aside, almost all toxicants, single or mixed and however altered, have …

The research landscape concerning environmental factors in neurodevelopmental disorders: Endocrine disrupters and pesticides—A review

RM Sánchez, JFB Losada, JAM Martínez - Frontiers in Neuroendocrinology, 2024 - Elsevier
In recent years, environmental epidemiology and toxicology have seen a growing interest in
the environmental factors that contribute to the increased prevalence of neurodevelopmental …

[HTML][HTML] Electrochemical sensing and bio-sensing of bisphenol A and detection of its damage to DNA: A comprehensive review

K Varmira, M Saed-Mocheshi, AR Jalalvand - Sensing and Bio-Sensing …, 2017 - Elsevier
This review is aimed at providing comprehensive information on the applications of
electrochemical sensors and biosensors to the determination of bisphenol A (BPA) and …

Low dose effects and nonmonotonic dose responses for endocrine disruptors

LN Vandenberg - Endocrine disruption and human health, 2022 - Elsevier
There are a number of features of endocrine-disrupting chemicals (EDCs) that distinguish
them from traditional toxicants. One such attribute is the ability of EDCs to induce …

Identification of potential bisphenol A (BPA) exposure biomarkers in ovarian cancer

A Zahra, Q Dong, M Hall, J Jeyaneethi, E Silva… - Journal of Clinical …, 2021 - mdpi.com
Endocrine-disrupting chemicals (EDCs) can exert multiple deleterious effects and have
been implicated in carcinogenesis. The xenoestrogen Bisphenol A (BPA) that is found in …