[HTML][HTML] Antineoplastic activity of biogenic silver and gold nanoparticles to combat leukemia: beginning a new era in cancer theragnostic
Abstract The American Cancer Society estimated around 61,090 new cases of leukemia
were diagnosed, and around 23,660 people died from this disease in the United States …
were diagnosed, and around 23,660 people died from this disease in the United States …
[HTML][HTML] The role of the thioredoxin detoxification system in cancer progression and resistance
M Jovanović, A Podolski-Renić, M Krasavin… - Frontiers in Molecular …, 2022 - frontiersin.org
The intracellular redox homeostasis is a dynamic balancing system between the levels of
free radical species and antioxidant enzymes and small molecules at the core of cellular …
free radical species and antioxidant enzymes and small molecules at the core of cellular …
Silver complexes as anticancer agents: A perspective review
SK Raju, A Karunakaran, S Kumar, P Sekar… - German Journal of …, 2022 - gjpb.de
Metal complexes gained more attention in the medical field, particularly cancer treatment,
due to their enhanced potential and redox ability. These complexes exhibited more …
due to their enhanced potential and redox ability. These complexes exhibited more …
[HTML][HTML] Gold-based metal drugs as inhibitors of coronavirus proteins: The inhibition of sars-cov-2 main protease by auranofin and its analogs
Gold compounds have a long tradition in medicine and offer many opportunities for new
therapeutic applications. Herein, we evaluated the lead compound Auranofin and five …
therapeutic applications. Herein, we evaluated the lead compound Auranofin and five …
[HTML][HTML] Antileukemia Activity and Mechanism of Platinum (II)-Based Metal Complexes
ML Di Pietro, C Stagno, T Efferth, EA Omer, V D'Angelo… - Molecules, 2022 - mdpi.com
Transition metal complexes have continued to constitute an appealing class of medicinal
compounds since the exceptional discovery of cisplatin in the late 1960s. Pt (II)-based …
compounds since the exceptional discovery of cisplatin in the late 1960s. Pt (II)-based …
Investigation of the influence of chirality and halogen atoms on the anticancer activity of enantiopure palladium (II) complexes derived from chiral amino-alcohol Schiff …
In continuation of our work on the synthesis of heteroleptic enantiopure Pd (II)-complexes,
four mixed-ligand enantiomeric pairs of Pd (II) complexes (J1–J8),[Pd (pic)(R or S)-N-(2, 3 …
four mixed-ligand enantiomeric pairs of Pd (II) complexes (J1–J8),[Pd (pic)(R or S)-N-(2, 3 …
Synthesis, chemical characterization, and biological evaluation of a novel auranofin derivative as an anticancer agent
A novel gold (I) complex inspired by the known medicinal inorganic compounds auranofin
and thimerosal, namely ethylthiosalicylate (triethylphosphine) gold (I)(AFETT hereafter), was …
and thimerosal, namely ethylthiosalicylate (triethylphosphine) gold (I)(AFETT hereafter), was …
Design, synthesis, and preclinical activity in ovarian cancer models of new phosphanegold (I)-N-heterocyclic carbene complexes
AAA Sulaiman, N Casagrande… - Journal of Medicinal …, 2022 - ACS Publications
A new series of seven gold (I) complexes (1–7) containing 1, 3-bis (2, 6-diisopropylphenyl)
imidazol-2-ylidene (IPr) and phosphane ligands (L1–L7) were synthesized and evaluated …
imidazol-2-ylidene (IPr) and phosphane ligands (L1–L7) were synthesized and evaluated …
Kinetic and structural analysis of the inactivation of urease by mixed-ligand phosphine halide Ag (I) complexes
Soft metal ions can inactivate urease, a Ni (II)-dependent enzyme whose hydrolytic activity
has significant implications in agro-environmental science and human health. Kinetic and …
has significant implications in agro-environmental science and human health. Kinetic and …
Modulatory Activity of the Copper Chelate, Copper N-(2-Hydroxy Acetophenone) Glycinate, in ABC-transporter-expressing Cell Lines
EM Hartinger, A Mahringer, SK Choudhuri… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: Metal-containing compounds (eg, platinum complexes) belong to the
standard armamentarium of cancer chemotherapy. Copper N-(2-hydroxy acetophenone) …
standard armamentarium of cancer chemotherapy. Copper N-(2-hydroxy acetophenone) …