[HTML][HTML] Antineoplastic activity of biogenic silver and gold nanoparticles to combat leukemia: beginning a new era in cancer theragnostic

E Mostafavi, A Zarepour, H Barabadi, A Zarrabi… - Biotechnology …, 2022 - Elsevier
Abstract The American Cancer Society estimated around 61,090 new cases of leukemia
were diagnosed, and around 23,660 people died from this disease in the United States …

[HTML][HTML] The role of the thioredoxin detoxification system in cancer progression and resistance

M Jovanović, A Podolski-Renić, M Krasavin… - Frontiers in Molecular …, 2022 - frontiersin.org
The intracellular redox homeostasis is a dynamic balancing system between the levels of
free radical species and antioxidant enzymes and small molecules at the core of cellular …

Silver complexes as anticancer agents: A perspective review

SK Raju, A Karunakaran, S Kumar, P Sekar… - German Journal of …, 2022 - gjpb.de
Metal complexes gained more attention in the medical field, particularly cancer treatment,
due to their enhanced potential and redox ability. These complexes exhibited more …

[HTML][HTML] Gold-based metal drugs as inhibitors of coronavirus proteins: The inhibition of sars-cov-2 main protease by auranofin and its analogs

L Massai, D Grifagni, A De Santis, A Geri, F Cantini… - Biomolecules, 2022 - mdpi.com
Gold compounds have a long tradition in medicine and offer many opportunities for new
therapeutic applications. Herein, we evaluated the lead compound Auranofin and five …

[HTML][HTML] Antileukemia Activity and Mechanism of Platinum (II)-Based Metal Complexes

ML Di Pietro, C Stagno, T Efferth, EA Omer, V D'Angelo… - Molecules, 2022 - mdpi.com
Transition metal complexes have continued to constitute an appealing class of medicinal
compounds since the exceptional discovery of cisplatin in the late 1960s. Pt (II)-based …

Investigation of the influence of chirality and halogen atoms on the anticancer activity of enantiopure palladium (II) complexes derived from chiral amino-alcohol Schiff …

HA Rudbari, N Kordestani, JV Cuevas-Vicario… - New Journal of …, 2022 - pubs.rsc.org
In continuation of our work on the synthesis of heteroleptic enantiopure Pd (II)-complexes,
four mixed-ligand enantiomeric pairs of Pd (II) complexes (J1–J8),[Pd (pic)(R or S)-N-(2, 3 …

Synthesis, chemical characterization, and biological evaluation of a novel auranofin derivative as an anticancer agent

D Cirri, L Massai, C Giacomelli, ML Trincavelli… - Dalton …, 2022 - pubs.rsc.org
A novel gold (I) complex inspired by the known medicinal inorganic compounds auranofin
and thimerosal, namely ethylthiosalicylate (triethylphosphine) gold (I)(AFETT hereafter), was …

Design, synthesis, and preclinical activity in ovarian cancer models of new phosphanegold (I)-N-heterocyclic carbene complexes

AAA Sulaiman, N Casagrande… - Journal of Medicinal …, 2022 - ACS Publications
A new series of seven gold (I) complexes (1–7) containing 1, 3-bis (2, 6-diisopropylphenyl)
imidazol-2-ylidene (IPr) and phosphane ligands (L1–L7) were synthesized and evaluated …

Kinetic and structural analysis of the inactivation of urease by mixed-ligand phosphine halide Ag (I) complexes

L Mazzei, D Cirri, M Cianci, L Messori… - Journal of inorganic …, 2021 - Elsevier
Soft metal ions can inactivate urease, a Ni (II)-dependent enzyme whose hydrolytic activity
has significant implications in agro-environmental science and human health. Kinetic and …

Modulatory Activity of the Copper Chelate, Copper N-(2-Hydroxy Acetophenone) Glycinate, in ABC-transporter-expressing Cell Lines

EM Hartinger, A Mahringer, SK Choudhuri… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: Metal-containing compounds (eg, platinum complexes) belong to the
standard armamentarium of cancer chemotherapy. Copper N-(2-hydroxy acetophenone) …