Malignant hematopoietic cell lines: in vitro models for the study of natural killer cell leukemia–lymphoma
HG Drexler, Y Matsuo - Leukemia, 2000 - nature.com
Malignancies involving natural killer (NK) cells are rare disorders. The complexity of NK cell-
involving disorders has only recently been appreciated. Modern classifications discern …
involving disorders has only recently been appreciated. Modern classifications discern …
Granulocyte colony-stimulating factor activation of Stat3 alpha and Stat3 beta in immature normal and leukemic human myeloid cells
A Chakraborty, SM White, TS Schaefer, ED Ball… - 1996 - ashpublications.org
Granulocyte colony-stimulating factor (G-CSF) is the cytokine critical for directing
neutrophilic granulocyte differentiation. Acute myelogenous leukemia (AML) cells, which …
neutrophilic granulocyte differentiation. Acute myelogenous leukemia (AML) cells, which …
Growth factor requirements of childhood acute T-lymphoblastic leukemia: correlation between presence of chromosomal abnormalities and ability to grow permanently …
R O'Connor, A Cesano, B Lange, J Finan, PC Nowell… - 1991 - ashpublications.org
Cells from 10 cases of childhood acute T-lymphoblastic leukemia (T-ALL) were cultured in
the presence of recombinant human interleukins (rhIL) or colony-stimulating factors (CSF) to …
the presence of recombinant human interleukins (rhIL) or colony-stimulating factors (CSF) to …
Two unique human leukemic T-cell lines endowed with a stable cytotoxic function and a different spectrum of target reactivity analysis and modulation of their lytic …
A Cesano, D Santoli - In Vitro Cellular & Developmental Biology-Animal, 1992 - Springer
We have reported the establishment of two interleukin (IL)-2-dependent human leukemic
cell lines (TALL-103/2 [CD3+ TCR γδ+] and TALL-104 [CD3+ TCR αβ+]) which display major …
cell lines (TALL-103/2 [CD3+ TCR γδ+] and TALL-104 [CD3+ TCR αβ+]) which display major …
Homing and progression patterns of childhood acute lymphoblastic leukemias in severe combined immunodeficiency mice
A Cesano, R O'Connor, B Lange, J Finan, G Rovera… - 1991 - ashpublications.org
The aim of this study was to analyze the homing and progression patterns of childhood
acute lymphoblastic leukemias (ALL) in mice with severe combined immunodeficiency …
acute lymphoblastic leukemias (ALL) in mice with severe combined immunodeficiency …
Leukemic cells and the cytokine patchwork
C Kiss, I Benkő, P Kovács - Pediatric blood & cancer, 2004 - Wiley Online Library
Background In leukemia, the clonal population is characterized by a hierarchical
organization. Although the majority of the leukemic population is generated after post …
organization. Although the majority of the leukemic population is generated after post …
Cytotoxic T-ALL cell lines and uses therefor
D Santoli, G Rovera, A Cesano - US Patent 5,272,082, 1993 - Google Patents
BACKGROUND OF THE INVENTION Within the past ten years, a new therapeutic regimen,
called LAK therapy, has been designed for the treat ment of solid tumors. According to LAX …
called LAK therapy, has been designed for the treat ment of solid tumors. According to LAX …
Inducible expression of granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-α, and interferon-γ in two human cytotoxic leukemic T-cell lines
A Cesano, D Santoli - In Vitro Cellular & Developmental Biology-Animal, 1992 - Springer
We investigated the ability of the TALL-103/2 and TALL-104 leukemic cell lines to produce
lymphokines in response to activation signals, such as tumor cells and anti-CD3 (OKT3) or …
lymphokines in response to activation signals, such as tumor cells and anti-CD3 (OKT3) or …
Growth factor-dependent differentiation along the myeloid and lymphoid lineages in an immature acute T lymphocytic leukemia.
R O'Connor, A Cesano, BL Kreider… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
Bone marrow cells from a child with an immature (CD2+, CD5+, CD7+) acute T lymphocytic
leukemia (T-ALL) were cultured in the presence and absence of human rIL-2, IL-3, or …
leukemia (T-ALL) were cultured in the presence and absence of human rIL-2, IL-3, or …
Interleukin 4 inhibits IL-2-induced proliferation of a human T-leukemia cell line without interfering with p56-LCK kinase activation
T Torigoe, R O'Connor, R Fagard, S Fischer, D Santoli… - Cytokine, 1992 - Elsevier
Recently we described the establishment in culture and the immunophenotypic and
functional characteristics of a human T-leukemia line TALL-103/2 derived from the T-cell …
functional characteristics of a human T-leukemia line TALL-103/2 derived from the T-cell …