Measurement of clinical and subclinical tumour response using [18F]-fluorodeoxyglucose and positron emission tomography: review and 1999 EORTC …

H Young, R Baum, U Cremerius, K Herholz… - European journal of …, 1999 - Elsevier
[18F]-fluorodeoxyglucose ([18F]-FDG) uptake is enhanced in most malignant tumours which
in turn can be measured using positron emission tomography (PET). A number of small …

Early detection of lung cancer: clinical perspectives of recent advances in biology and radiology

FR Hirsch, WA Franklin, AF Gazdar, PA Bunn Jr - Clinical Cancer Research, 2001 - AACR
Lung cancer is the most common cause of cancer death in developed countries. The
prognosis is poor, with less than 15% of patients surviving 5 years after diagnosis. The poor …

ATP citrate lyase: activation and therapeutic implications in non–small cell lung cancer

T Migita, T Narita, K Nomura, E Miyagi, F Inazuka… - Cancer research, 2008 - AACR
Enhanced glucose and lipid metabolism is one of the most common properties of malignant
cells. ATP citrate lyase (ACLY) is a key enzyme of de novo fatty acid synthesis responsible …

Screening for early lung cancer with low-dose spiral CT: prevalence in 817 asymptomatic smokers

S Diederich, D Wormanns, M Semik, M Thomas… - Radiology, 2002 - pubs.rsna.org
PURPOSE: To present prevalence screening data from a nonrandomized screening trial by
using low-dose computed tomography (CT) and a simple algorithm based on the size and …

PET/CT: Form and Function1

TM Blodgett, CC Meltzer, DW Townsend - Radiology, 2007 - pubs.rsna.org
Functional imaging with positron emission tomography (PET) is playing an increasingly
important role in the diagnosis and staging of malignant disease, image-guided therapy …

Positron emission tomography is superior to computed tomography scanning for response-assessment after radical radiotherapy or chemoradiotherapy in patients …

MP Mac Manus, RJ Hicks, JP Matthews… - Journal of Clinical …, 2003 - ascopubs.org
Purpose: To prospectively study the capacity of positron emission tomography (PET) and
computed tomography (CT) to determine response soon after radical radiotherapy or …

PET imaging in oncology

R Bar-Shalom, AY Valdivia, MD Blaufox - Seminars in nuclear medicine, 2000 - Elsevier
The role of positron emission tomography (PET) during the past decade has evolved rapidly
from a pure research tool to a methodology of enormous clinical potential. Perhaps the most …

Evaluation of F-18 fluorodeoxyglucose (FDG) PET scanning for pulmonary nodules less than 3 cm in diameter, with special reference to the CT images

H Nomori, K Watanabe, T Ohtsuka, T Naruke… - Lung cancer, 2004 - Elsevier
Background: While pulmonary nodules can be substantially divided into solid and ground-
glass opacity (GGO) ones on CT image, they have different biological natures which could …

Comparison between positron emission tomography and computed tomography in the use of the assessment of esophageal carcinoma

H Kato, H Kuwano, M Nakajima, T Miyazaki… - Cancer, 2002 - Wiley Online Library
BACKGROUND The role and potential value of positron emission tomography (PET)
scanning in certain tumors has been widely investigated in recent years. The authors …

From tumor biology to clinical PET: a review of positron emission tomography (PET) in oncology

K Kubota - Annals of nuclear medicine, 2001 - Springer
Cancer cells show increased metabolism of both glucose and amino acids, which can be
monitored with 18 F-2-deoxy-2-fluoro-d-glucose (FDG), a glucose analogue, and 11 Cl …