[HTML][HTML] The antioxidant transcription factor Nrf2 in cardiac ischemia–reperfusion injury

A Mata, S Cadenas - International journal of molecular sciences, 2021 - mdpi.com
Nuclear factor erythroid-2 related factor 2 (Nrf2) is a transcription factor that controls cellular
defense responses against toxic and oxidative stress by modulating the expression of genes …

Isoproterenol‐induced cardiac ischemia and fibrosis: Plant‐based approaches for intervention

P Allawadhi, A Khurana, N Sayed… - Phytotherapy …, 2018 - Wiley Online Library
Heart is the most active and incumbent organ of the body, which maintains blood flow, but
due to various pathological reasons, several acute and chronic cardiac complications arise …

Beneficial effects of Chrysin on Cadmium‐induced nephrotoxicity in rats: Modulating the levels of Nrf2/HO‐1, RAGE/NLRP3, and Caspase-3/Bax/Bcl-2 signaling …

H Şimşek, N Akaras, C Gür, S Küçükler, FM Kandemir - Gene, 2023 - Elsevier
Cadmium (Cd) is a toxic heavy metal that targets the kidney directly in the body. Chrysin
(CHR) is a natural flavonoid with many properties such as antioxidant, anti-inflammatory and …

[HTML][HTML] Cecal gut microbiota and metabolites might contribute to the severity of acute myocardial ischemia by impacting the intestinal permeability, oxidative stress …

L Sun, H Jia, J Li, M Yu, Y Yang, D Tian… - Frontiers in …, 2019 - frontiersin.org
Emerging evidence highlights the role of gut microbiota in regulating the pathogenesis of
coronary heart disease. Here, we performed 16S rRNA gene sequencing and UPLC-Q …

Molecular understanding of the protective role of natural products on isoproterenol-induced myocardial infarction: A review

ZW Wong, PV Thanikachalam… - Biomedicine & …, 2017 - Elsevier
Modern medicine has been used to treat myocardial infarction, a subset of cardiovascular
diseases, and have been relatively effective but not without adverse effects. Consequently …

[HTML][HTML] Protective effect of geraniol on oxidative, inflammatory and apoptotic alterations in isoproterenol-induced cardiotoxicity: role of the Keap1/Nrf2/HO-1 and PI3K …

NS Younis, MS Abduldaium, ME Mohamed - Antioxidants, 2020 - mdpi.com
Background: Myocardial infarction (MI) is still a major contributor to mortality worldwide, and
therefore, searching for new drugs is an urgent priority. Natural products are a renewable …

Protective effects of sinapic acid against lead acetate-induced nephrotoxicity: a multi-biomarker approach

H Şimşek, S Küçükler, C Gür, N Akaras… - … Science and Pollution …, 2023 - Springer
Lead acetate (PbAc) is one of the top five most dangerous toxic heavy metals, particularly
leading to kidney damage and posing serious health risks in both humans and animals …

[HTML][HTML] Multiomics analysis of soybean meal induced marine fish enteritis in juvenile pearl gentian grouper, Epinephelus fuscoguttatus♀× Epinephelus lanceolatus♂

W Zhang, B Tan, J Deng, Z Haitao - Scientific Reports, 2021 - nature.com
As an important protein source, soybean products can cause intestinal inflammation and
injury in many animals including human beings, particularly infants and juvenile individuals …

Role of MAPK/NF-κB pathway in cardioprotective effect of Morin in isoproterenol induced myocardial injury in rats

VK Verma, S Malik, SP Narayanan, E Mutneja… - Molecular biology …, 2019 - Springer
Oxidative stress plays a major role in myocardial injury. Morin, a bioflavonoid has known to
possess various biological activities in previous studies. Hence, this study evaluated the …

Cardioprotective Effects of Aconite in Isoproterenol‐Induced Myocardial Infarction in Rats

Z Xing, C Yang, J He, Y Feng, X Li… - … medicine and cellular …, 2022 - Wiley Online Library
Background. Myocardial infarction (MI) is a severe clinical condition caused by decreased or
complete cessation of blood flow to a portion of the myocardium. Aconite, the lateral roots of …