The exclusive expression of uromodulin in the kidneys has made it an intriguing protein in
kidney and cardiovascular research. Genome-wide association studies discovered variants …

Background: Salt sensitivity of blood pressure (SSBP) is a trait observed in both humans and
animals, characterized by an increase in blood pressure (BP) following salt loading or a …

Objective Renalase, a novel secretory flavoprotein with amine oxidase activity, is secreted
into the blood by the kidneys and is hypothesized to participate in blood pressure (BP) …

Background: Acute kidney injury (AKI) is a severe condition marked by rapid renal function
deterioration and elevated mortality, with traditional biomarkers lacking sensitivity and …

Uromodulin, also referred to as Tamm Horsfall protein (THP), is a renal protein exclusively
synthesized by the kidneys and represents the predominant urinary protein under normal …

目的通过对本课题组早期建立的“盐敏感性高血压研究队列” 进行钠钾饮食干预,
旨在探讨人群尿调节素基因多态性与血压钠钾反应性的关系. 方法2004 年在陕西眉县招募的 …

The E‐proteinoid 3 receptor (PTGER3), a member of the prostaglandin E2 (PGE2) subtype
receptor, belongs to the G‐protein‐coupled superfamily of receptors. Animal studies have …

Background Pregnancy involves major adaptations in renal haemodynamics, tubular, and
endocrine functions. Hypertensive disorders of pregnancy are a leading cause of maternal …

Uromodulin is a kidney-specific glycoprotein which is exclusively produced by the epithelial
cells lining the thick ascending limb and early distal convoluted tubule. It is currently …

Background: Hyperuricemia can lead to nephrolithiasis and gout. It is an essential indicator
of diseases like metabolic syndrome, cardiovascular disease, diabetes mellitus, and chronic …