HIV-1 Nef and KSHV oncogene K1 synergistically promote angiogenesis by inducing cellular miR-718 to regulate the PTEN/AKT/mTOR signaling pathway

M Xue, S Yao, M Hu, W Li, T Hao, F Zhou… - Nucleic acids …, 2014 - academic.oup.com
Kaposi's sarcoma (KS) is an AIDS-defining cancer with aberrant neovascularization caused
by KS-associated herpesvirus (KSHV). Although the interaction between HIV-1 and KSHV …

[HTML][HTML] PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations

H Blesinger, S Kaulfuß, T Aung, S Schwoch, L Prantl… - PLoS …, 2018 - journals.plos.org
Lymphatic malformations (LM) are characterized by the overgrowth of lymphatic vessels
during pre-and postnatal development. Macrocystic, microcystic and combined forms of LM …

The regulation of cancer cell death and metabolism by extracellular matrix attachment

CL Buchheit, RR Rayavarapu, ZT Schafer - Seminars in cell & …, 2012 - Elsevier
The metastasis of cancer cells to distant sites is responsible for the vast majority of cancer
mortalities yet the molecular mechanisms underlying this extraordinarily complicated …

Melatonin inhibits reactive oxygen species‐driven proliferation, epithelial‐mesenchymal transition, and vasculogenic mimicry in oral cancer

R Liu, H Wang, M Deng, X Wen, Y Mo… - Oxidative Medicine …, 2018 - Wiley Online Library
Globally, oral cancer is the most common type of head and neck cancers. Melatonin elicits
inhibitory effects on oral cancer; however, the biological function of melatonin and …

New insights in sarcoma oncogenesis: a comprehensive analysis of a large series of 160 soft tissue sarcomas with complex genomics

L Gibault, G Pérot, F Chibon, S Bonnin… - The Journal of …, 2011 - Wiley Online Library
Adult soft tissue sarcomas (STS) are rare tumours of mesenchymal lineage. Based on
cytogenetic and comparative genomic hybridization (CGH) data, they can be divided into …

Hepatitis B virus small envelope protein promotes hepatocellular carcinoma angiogenesis via endoplasmic reticulum stress signaling to upregulate the expression of …

SX Wu, SS Ye, YX Hong, Y Chen, B Wang… - Journal of …, 2022 - Am Soc Microbiol
Hepatocellular carcinoma (HCC) is a hypervascular tumor, and accumulating evidence has
indicated that stimulation of angiogenesis by hepatitis B virus (HBV) may contribute to HCC …

Chromosomal instability as enabling feature and central hallmark of breast cancer

G Castellanos, DS Valbuena, E Pérez… - … Cancer: Targets and …, 2023 - Taylor & Francis
Chromosomal instability (CIN) has become a topic of great interest in recent years, not only
for its implications in cancer diagnosis and prognosis but also for its role as an enabling …

PI3K/Akt/mTOR signaling pathway and the biphasic effect of arsenic in carcinogenesis

QY Chen, M Costa - Molecular pharmacology, 2018 - ASPET
Arsenic is a naturally occurring, ubiquitous metalloid found in the Earth's crust. In its
inorganic form, arsenic is highly toxic and carcinogenic and is widely found across the globe …

Mechanisms of nitric oxide-mediated inhibition of EMT in cancer: inhibition of the metastasis-inducer Snail and induction of the metastasis-suppressor RKIP

S Baritaki, S Huerta-Yepez, A Sahakyan… - Cell cycle, 2010 - Taylor & Francis
The role of nitric oxide (NO) in cancer has been controversial and is based on the levels of
NO and the responsiveness of the tumor type. It remains unclear whether NO can inhibit the …

[HTML][HTML] HIV-1 Tat promotes Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6-induced angiogenesis and tumorigenesis by regulating PI3K/PTEN/AKT/GSK-3β …

F Zhou, M Xue, D Qin, X Zhu, C Wang, J Zhu, T Hao… - PloS one, 2013 - journals.plos.org
Kaposi's sarcoma (KS)-associated herpesvirus (KSHV) is etiologically associated with KS,
the most common AIDS-related malignancy. KS is characterized by vast angiogenesis and …