The myriad of peptides presented at the cell surface by class I and class II major
histocompatibility complex (MHC) molecules are referred to as the immunopeptidome and …

Antigen presentation lies at the heart of immune recognition of infected or malignant cells.
For this reason, important efforts have been made to predict which peptides are more likely …

Peptide antigens bound to molecules encoded by the major histocompatibility complex
(MHC) and presented on the cell surface form the targets of T lymphocytes. This critical arm …

The entirety of human leukocyte antigen (HLA)‐presented peptides is referred to as the HLA
ligandome of a cell or tissue, in tumours often termed immunopeptidome. Mapping the …

Current knowledge about the dynamics of antigen presentation to T cells during viral
infection is very poor despite being of fundamental importance to our understanding of anti …

Objective The association of HLA–B27 with spondyloarthropathy is one of the strongest
documented for any autoimmune disease. A common hypothesis for this association is the …

Peptides presented by human leukocyte antigen (HLA) molecules on the cell surface play a
crucial role in adaptive immunology, mediating the communication between T cells and …

The immunopeptidome is the repertoire of peptides bound and presented by the MHC class
I, class II, and non-classical molecules. The peptides are produced by the degradation of …

According to the latest available data, cancer is the second leading cause of death,
highlighting the need for novel cancer therapeutic approaches. In this context …

Human leukocyte antigen (HLA) class I molecules generally present peptides (p) of 8 to 11
amino acids (aa) in length. Although an increasing number of examples with lengthy (> 11 …