Postoperative delirium is a relatively common and serious complication. It increases hospital
stay by 2–3 days and is associated with a 30-day mortality of 7–10%. It is most prevalent in …

Rats and mice are used for studying neuronal circuits underlying recognition memory due to
their ability to spontaneously remember the occurrence of an object, its place and an …

Learning and memory are assumed to be supported by mechanisms that involve cholinergic
transmission and hippocampal theta. Using G protein–coupled receptor-activation–based …

Background Alzheimer's disease (AD) is the most common type of dementia and seriously
affects human life and health. Kaempferol (KMP) is a common flavonoid, that is mainly …

Acetylcholine plays an essential role in fundamental aspects of cognition. Studies that have
mapped the activity and functional connectivity of cholinergic neurons have shown that the …

Aging is a complex biological process that increases the risk of age-related cognitive
degenerative diseases such as dementia, including Alzheimer's disease (AD), Lewy Body …

Acetylcholine (ACh), released in the hippocampus from fibers originating in the medial
septum/diagonal band of Broca (MSDB) complex, is crucial for learning and memory. The …

Alcoholism is associated with brain damage and impaired cognitive functioning. The relative
contributions of different etiological factors, such as alcohol, thiamine deficiency and age …

Background Imbalanced synaptic transmission appears to be an early driver in Alzheimer's
disease (AD) leading to brain network alterations. Early detection of altered synaptic …

Background Mounting evidence indicates that stem cell-derived exosomal miRNAs have
therapeutic effects on traumatic brain injury (TBI). This research is focused on exploring the …