[HTML][HTML] Quantification of brain oxygen extraction and metabolism with [15O]-gas PET: A technical review in the era of PET/MRI

AP Fan, H An, F Moradi, J Rosenberg, Y Ishii, T Nariai… - Neuroimage, 2020 - Elsevier
Oxygen extraction fraction (OEF) and the cerebral metabolic rate of oxygen (CMRO 2) are
key cerebral physiological parameters to identify at-risk cerebrovascular patients and …

Myocardial energetics and efficiency: current status of the noninvasive approach

P Knaapen, T Germans, J Knuuti, WJ Paulus… - Circulation, 2007 - Am Heart Assoc
It is important to realize that 2 stages can be distinguished in the process of MVo2
conversion to mechanical energy:(1) efficiency of energy transfer from MVo2 to total PVA …

[HTML][HTML] Human brown adipose tissue [15O]O2 PET imaging in the presence and absence of cold stimulus

M u Din, J Raiko, T Saari, N Kudomi, T Tolvanen… - European Journal of …, 2016 - Springer
Purpose Brown adipose tissue (BAT) is considered a potential target for combatting obesity,
as it produces heat instead of ATP in cellular respiration due to uncoupling protein-1 (UCP …

Database of normal human cerebral blood flow, cerebral blood volume, cerebral oxygen extraction fraction and cerebral metabolic rate of oxygen measured by …

H Ito, I Kanno, C Kato, T Sasaki, K Ishii, Y Ouchi… - European journal of …, 2004 - Springer
Measurement of cerebral blood flow (CBF), cerebral blood volume (CBV), cerebral oxygen
extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO 2) by positron …

Morning-evening variation in human brain metabolism and memory circuits

BJ Shannon, RA Dosenbach, Y Su… - Journal of …, 2013 - journals.physiology.org
It has been posited that a critical function of sleep is synaptic renormalization following a net
increase in synaptic strength during wake. We hypothesized that wake would alter the …

Oxidative and nonoxidative metabolism of excited neurons and astrocytes

A Gjedde, S Marrett, M Vafaee - Journal of cerebral blood …, 2002 - journals.sagepub.com
There is evidence that the metabolic responses to afferent and efferent nervous activity are
dissociated at sites of neuronal excitation in brain. Whether efferent activity follows afferent …

Quantification of cerebral blood flow and oxygen metabolism with 3-dimensional PET and 15O: validation by comparison with 2-dimensional PET

M Ibaraki, S Miura, E Shimosegawa… - Journal of Nuclear …, 2008 - Soc Nuclear Med
Quantitative PET with 15O provides absolute values for cerebral blood flow (CBF), cerebral
blood volume (CBV), cerebral metabolic rate of oxygen (CMRO2), and oxygen extraction …

Validation of T2‐based oxygen extraction fraction measurement with 15O positron emission tomography

D Jiang, S Deng, CG Franklin, M O'Boyle… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose To evaluate the accuracy of T2‐based whole‐brain oxygen extraction fraction
(OEF) estimation by comparing it with gold standard 15O‐PET measurements. Methods …

Evaluation of Basis Function and Linear Least Squares Methods for Generating Parametric Blood Flow Images Using 15O-Water and Positron Emission Tomography

R Boellaard, P Knaapen, A Rijbroek… - Molecular Imaging and …, 2005 - Springer
Purpose Parametric analysis of 15 O-water positron emission tomography (PET) studies
allows determination of blood flow (BF), perfusable tissue fraction (PTF), and volume of …

Interindividual variations of cerebral blood flow, oxygen delivery, and metabolism in relation to hemoglobin concentration measured by positron emission tomography …

M Ibaraki, Y Shinohara, K Nakamura… - Journal of Cerebral …, 2010 - journals.sagepub.com
Regional cerebral blood flow (CBF) and oxygen metabolism can be measured by positron
emission tomography (PET) with 15O-labeled compounds. Hemoglobin (Hb) concentration …