Abstract The latest French Guidelines for the management in the first 24 hours of patients
with severe traumatic brain injury (TBI) were published in 1998. Due to recent changes …

Objective To report the ESICM consensus and clinical practice recommendations on fluid
therapy in neurointensive care patients. Design A consensus committee comprising 22 …

Background Acute treatment of cerebral edema and elevated intracranial pressure is a
common issue in patients with neurological injury. Practical recommendations regarding …

Objectives: Hypocapnia is used in the management of acute brain injury and may be life-
saving in specific circumstances, but it can produce neuronal ischemia and injury, potentially …

During traumatic brain injury, intracranial hypertension (ICH) can become a life-threatening
condition if it is not managed quickly and adequately. Physicians use therapeutic …

The potential superiority of hypertonic saline (HTS) over mannitol (MTL) for control of
intracranial pressure (ICP) following traumatic brain injury (TBI) is still debated. Forty-seven …

Objective In neurotrauma care, a better understanding of treatments after traumatic brain
injury (TBI) has led to a significant decrease in morbidity and mortality in this population. TBI …

The term 'brain relaxation'is routinely used to describe the size and firmness of the brain
tissue during craniotomy. The status of brain relaxation is an important aspect of …

Although hyperventilation is commonly applied in patients with TBI or intracranial
hemorrhage or in those undergoing craniotomy, its effects on patient outcomes have not …

Background This prospective randomized controlled study compared the efficacy of an
equiosmolar and isovolumetric dose of 3% hypertonic saline, 20% mannitol, and 10 …