Aging is an inevitable natural process that impacts every individual, and understanding its
effect on the gut microbiome and dendritic cell (DC) functionality in elderly subjects is …

Osteoporosis is a common chronic metabolic bone disorder. Recently, increasing numbers
of studies have demonstrated that Toll-like receptor 4 (TLR4, a receptor located on the …

Macrophages play a pivotal role in safeguarding against a broad spectrum of infections,
from viral, bacterial, fungal to parasitic threats and contributing to the immune defense …

Millions of people suffer globally from disorders caused by narcotic substances. Drug
addiction leads to the destruction of an individual's life and risk to public safety. Morphine is …

Morphine addiction poses a significant challenge to global healthcare. Current opioid
substitution therapies, such as buprenorphine, naloxone and methadone are effective but …

Excessive extracellular matrix (ECM) deposition is a defining feature of cardiac fibrosis. Most
notably, it is characterized by a significant change in the concentration and volume fraction …

Human immunodeficiency virus (HIV) infection is still a global public health issue, and the
development of an effective prophylactic vaccine inducing potent neutralizing antibodies …