Immunosuppressive tumor microenvironment and uterine fibroids: Role in collagen synthesis

EE Abd EL-Fattah, R Michel, MA Borahay - Cytokine & Growth Factor …, 2023 - Elsevier
Uterine fibroids (UF), also called uterine leiomyoma, is one of the most prevalent uterine
tumors. UF represents a serious women's health global problem with a significant physical …

[HTML][HTML] Progesterone signaling and uterine fibroid pathogenesis; molecular mechanisms and potential therapeutics

M Ali, M Ciebiera, S Vafaei, S Alkhrait, HY Chen… - Cells, 2023 - mdpi.com
Uterine fibroids (UFs) are the most important benign neoplastic threat to women's health
worldwide, with a prevalence of up to 80% in premenopausal women, and can cause heavy …

Contemporary evaluation of women and girls with abnormal uterine bleeding: FIGO Systems 1 and 2

V Jain, MG Munro, HOD Critchley - International Journal of …, 2023 - Wiley Online Library
Abnormal uterine bleeding (AUB) is common, often debilitating, and may affect over 50% of
reproductive‐aged women and girls. Whereas AUB is a collection of symptoms that include …

A Decision‐Making Framework Based on 2‐Tuple Linguistic Fermatean Fuzzy Hamy Mean Operators

M Akram, R Bibi… - Mathematical Problems in …, 2022 - Wiley Online Library
Aggregation operators are useful tools for approaching situations in the realm of
multiattribute decision‐making (MADM). Among the most valuable aggregation strategies …

[HTML][HTML] Global, regional, and national time trends in incidence, prevalence, years lived with disability for uterine fibroids, 1990–2019: an age-period-cohort analysis …

Z Lou, Y Huang, S Li, Z Luo, C Li, K Chu, T Zhang… - BMC Public Health, 2023 - Springer
Background Uterine fibroids are the most common benign neoplasm of the uterus and a
major source of morbidity for women. We report an overview of trends in uterine fibroids of …

[HTML][HTML] Phytochemical Profiling, Antioxidant, Anti-Inflammatory, Thrombolytic, Hemolytic Activity In Vitro and In Silico Potential of Portulacaria afra

S Tabassum, S Ahmad, K Rehman Khan, F Tabassum… - Molecules, 2022 - mdpi.com
The use of complementary herbal medicines has recently increased in an attempt to find
effective alternative therapies that reduce the adverse effects of chemical drugs. Portulacaria …

[HTML][HTML] Developmental reprogramming of myometrial stem cells by endocrine disruptor linking to risk of uterine fibroids

Q Yang, M Ali, LS Treviño, A Mas… - Cellular and Molecular Life …, 2023 - Springer
Background The stage, when tissues and organs are growing, is very vulnerable to
environmental influences, but it's not clear how exposure during this time causes changes to …

[HTML][HTML] Update on the role and regulatory mechanism of extracellular matrix in the pathogenesis of uterine fibroids

Q Yang, A Al-Hendy - International Journal of Molecular Sciences, 2023 - mdpi.com
Uterine fibroids (UFs), also known as leiomyomas, are benign tumors of the myometrium
affecting over 70% of women worldwide, particularly women of color. Although benign, UFs …

[HTML][HTML] Epigenetic modulation of inflammatory pathways in myometrial stem cells and risk of uterine fibroids

Q Yang, M Ali, LS Treviño, A Mas, N Ismail… - International Journal of …, 2023 - mdpi.com
The period during which tissue and organ development occurs is particularly vulnerable to
the influence of environmental exposures. However, the specific mechanisms through which …

Circulating inflammatory cytokines and female reproductive diseases: a Mendelian randomization analysis

Y Lin, G Wang, Y Li, H Yang, Y Zhao… - The Journal of Clinical …, 2023 - academic.oup.com
Context Extensive studies have provided considerable evidence suggesting the role of
inflammation in the development of female reproductive diseases. However, causality has …