[HTML][HTML] The role of cannabidiol in aging

B Ni, Y Liu, M Dai, J Zhao, Y Liang, X Yang… - Biomedicine & …, 2023 - Elsevier
Aging is usually considered a key risk factor associated with multiple diseases, such as
neurodegenerative diseases, cardiovascular diseases and cancer. Furthermore, the burden …

[HTML][HTML] The contribution of gut microbiota and endothelial dysfunction in the development of arterial hypertension in animal models and in humans

J Maiuolo, C Carresi, M Gliozzi, R Mollace… - International Journal of …, 2022 - mdpi.com
The maintenance of the physiological values of blood pressure is closely related to
unchangeable factors (genetic predisposition or pathological alterations) but also to …

[HTML][HTML] Cannabidiol improves antioxidant capacity and reduces inflammation in the lungs of rats with monocrotaline-induced pulmonary hypertension

A Krzyżewska, M Baranowska-Kuczko, A Jastrząb… - Molecules, 2022 - mdpi.com
Cannabidiol (CBD) is a plant-derived compound with antioxidant and anti-inflammatory
properties. Pulmonary hypertension (PH) is still an incurable disease. CBD has been …

[HTML][HTML] The Use of Cannabidiol in Metabolic Syndrome—An Opportunity to Improve the Patient's Health or Much Ado about Nothing?

M Wiciński, A Fajkiel-Madajczyk, Z Kurant… - Journal of Clinical …, 2023 - mdpi.com
Cannabis-derived therapies are gaining popularity in the medical world. More and more
perfect forms of cannabinoids are sought, which could be used in the treatment of many …

[HTML][HTML] Influence of Inhibition of COX-2-dependent lipid metabolism on regulation of UVB-induced keratinocytes apoptosis by cannabinoids

P Wójcik, M Biernacki, N Domian, N Žarković… - Biomolecules, 2022 - mdpi.com
Inflammation and apoptosis are regulated by similar factors, including ultraviolet B (UVB)
radiation and cannabinoids, which are metabolized by cyclooxygenase-2 (COX-2) into pro …

Pharmacognosy and effects of cannabinoids in the vascular system

E Mensah, R Tabrizchi… - ACS Pharmacology & …, 2022 - ACS Publications
Understanding the pharmacodynamics of cannabinoids is an essential subject due to the
recent increasing global acceptance of cannabis and its derivation for recreational and …

[HTML][HTML] Cannabidiol downregulates myocardial de novo ceramide synthesis pathway in a rat model of high-fat diet-induced obesity

T Charytoniuk, K Sztolsztener, P Bielawiec… - International Journal of …, 2022 - mdpi.com
It is known that metabolic disturbances, including obesity, predispose to an increased
incidence of cardiovascular diseases. Elevated consumption of dietary fat results in …

[HTML][HTML] Cannabidiol inhibits lung proliferation in monocrotaline-induced pulmonary hypertension in rats

A Krzyżewska, M Baranowska-Kuczko… - Biomedicine & …, 2023 - Elsevier
Cannabidiol (CBD) is a safe and well-tolerated plant-derived drug with anti-proliferative
properties. Pulmonary hypertension (PH) is a rapidly progressive and still incurable disease …

[HTML][HTML] Why multitarget vasodilatory (endo) cannabinoids are not effective as antihypertensive compounds after chronic administration: Comparison of their effects on …

P Remiszewski, B Malinowska - Pharmaceuticals, 2022 - mdpi.com
Systemic and pulmonary hypertension are multifactorial, high-pressure diseases. The first
one is a civilizational condition, and the second one is characterized by a very high mortality …

[HTML][HTML] Function of Presynaptic Inhibitory Cannabinoid CB1 Receptors in Spontaneously Hypertensive Rats and Its Modification by Enhanced Endocannabinoid …

M Toczek, E Schlicker, P Remiszewski… - International Journal of …, 2024 - mdpi.com
We studied whether the function of presynaptic inhibitory cannabinoid CB1 receptors on the
sympathetic nerve fibres innervating resistance vessels is increased in spontaneously …