Gaining insight into osmotic pressure and its biological implications is pivotal for revealing
mechanisms underlying numerous fundamental biological processes across scales and will …

The lateral diffusion of cell membrane inclusions, such as integral membrane proteins and
bound receptors, drives critical biological processes, including the formation of complexes …

The physical and chemical environment inside cells is of fundamental importance to all life
but has traditionally been difficult to determine on a subcellular basis. Here we combine …

The conversion of CO2 by enzymes such as carbonic anhydrase or carboxylases plays a
crucial role in many biological processes. However, in situ methods following the …

Simple Summary The aim of our study is to use E-selectin-binding peptide (ESBP) to actively
recognize E-selectin, so allowing a drug delivery system to actively recognize the cells and …

Methods Here we investigate the diffusion rate in three distinct locations in mesenchymal
cell types, namely the open cytoplasm, the stress fibers in the open cytoplasm, and those …

Cell division, aging, and stress recovery triggers spatial reorganization of cellular
components in the cytoplasm, including membrane bound organelles, with molecular …

DNA-linked gold nanoparticles (DNA-AuNPs) are combined nanomaterials that contain the
optical and electronic properties of AuNPs with the unique functions of DNA. These hybrid …

Molecular Dynamics simulations are often used in drug design. However, such simulations
do not account for the physiological environment of the receptor; hence overlook its impact …

Mammalian cells release a heterogeneous array of extracellular vesicles (EVs) that impact
human biology by contributing to intercellular communication. To resolve EV heterogeneity …