Chitooligosaccharides and their biological activities: A comprehensive review

F Liaqat, R Eltem - Carbohydrate polymers, 2018 - Elsevier
Chitin is the most abundant natural polysaccharide and chitosan is its most important
derivative. Regardless of having various bioactivities, the water insolubilities of chitin and …

The impact of chitooligosaccharides and their derivatives on the in vitro and in vivo antitumor activity: A comprehensive review

X Zhai, C Li, D Ren, J Wang, C Ma… - Carbohydrate Polymers, 2021 - Elsevier
Chitooligosaccharides (COS) are the degraded products of chitin or chitosan. COS is water-
soluble, non-cytotoxic to organisms, readily absorbed through the intestine, and eliminated …

An overview of fungal chitinases and their potential applications

D Thakur, A Bairwa, B Dipta, P Jhilta, A Chauhan - Protoplasma, 2023 - Springer
Chitin, the world's second most abundant biopolymer after cellulose, is composed of β-1, 4-
N-acetylglucosamine (GlcNAc) residues. It is the key structural component of many …

Chitooligosaccharide and Its Derivatives: Potential Candidates as Food Additives and Bioactive Components

A Mittal, A Singh, J Buatong, J Saetang, S Benjakul - Foods, 2023 - mdpi.com
Chitooligosaccharide (CHOS), a depolymerized chitosan, can be prepared via physical,
chemical, and enzymatic hydrolysis, or a combination of these techniques. The superior …

LincRNA‐p21 enhances the sensitivity of radiotherapy for gastric cancer by targeting the β‐catenin signaling pathway

L Chen, D Yuan, Y Yang, M Ren - Journal of cellular …, 2019 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a large and diverse class of transcribed RNA
molecules with a length of more than 200 nucleotides that modulate the gene expression at …

[HTML][HTML] LncRNA ANRIL negatively regulated chitooligosaccharide-induced radiosensitivity in colon cancer cells by sponging miR-181a-5p

C Sun, C Shen, Y Zhang, C Hu - Advances in Clinical and …, 2021 - advances.umw.edu.pl
Objectives. In this study, the lncRNA antisense non-coding RNA in the INK4 locus (ANRIL)
was selected to analyze its regulatory role in chitooligosaccharides (COS)-related …

Bioconversion of chitin to bioactive chitooligosaccharides: amelioration and coastal pollution reduction by microbial resources

M Kumar, A Brar, V Vivekanand, N Pareek - Marine Biotechnology, 2018 - Springer
Chitin-metabolizing products are of high industrial relevance in current scenario due to their
wide biological applications, relatively lower cost, greater abundance, and sustainable …

Production of N-acetyl chitooligosaccharide by novel Streptomyces chilikensis strain RC1830 and its evaluation for anti-radical, anti-inflammatory, anti-proliferative …

HT Behera, A Mojumdar, SR Das, S Jema… - Bioresource Technology …, 2020 - Elsevier
The present study focuses on the preparation of N-acetyl chitooligosaccharides (N-AcCOS)
by microbial degradation of colloidal chitin using novel Streptomyces chilikensis strain …

Effect of chitosan oligosaccharides on antioxidant function, lymphocyte cycle and apoptosis in ileum mucosa of broiler

LI Xiaocong, D Xuemei, P Xi… - Kafkas Üniversitesi …, 2017 - vetdergikafkas.org
The purpose of this study was to investigate the effects of chitosan oligosaccharides (COS)
on the antioxidative function, lymphocyte cycle and apoptosis of ileum mucosa in broiler …

[HTML][HTML] Chitooligosaccharides induce apoptosis in human breast cancer cells

MK Mallakuntla, V Penugurti, B Manavathi… - Carbohydrate Polymer …, 2021 - Elsevier
In this study, biologically active chitooligosaccharides (COS) D 3–7 (D-deacetylated unit)
and A 5 (A-acetylated unit) were assessed for their suitability to reduce the viability of human …