Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Mammalian studies have shaped our understanding of the endocrine control of appetite and
body weight in vertebrates and provided the basic vertebrate model that involves central …

Metabolic diseases are becoming increasingly common in modern society. Therefore, it is
essential to develop effective drugs or new treatments for metabolic diseases. As an active …

Spexin mRNA and protein are widely expressed in rat tissues and associate with weight loss
in rodents of diet-induced obesity. Its location in endocrine and epithelial cells has also been …

Cholangiocytes, epithelial cells that line the biliary epithelium, are the primary target cells for
cholangiopathies including primary sclerosing cholangitis and primary biliary cholangitis …

Background and aims Spexin (SPX) is a novel peptide recently discovered as an important
regulatory adipokine in obesity and related metabolic diseases. The aim of the current study …

Obesity may cause several metabolic complications, including insulin resistance and type 2
diabetes mellitus. Despite great advances in medicine, people still keep exploring novel and …

Obesity/overweight are important health problems due to metabolic complications.
Dysregulation of peptides exerting orexigenic/anorexigenic effects must be investigated in …

Overweight and obesity may cause several metabolic complications, including type 2
diabetes mellitus and hyperlipidemia. Despite years of progress in medicine, there are no …

Spexin is a newly discovered neuropeptide in vertebrates. Comprehensive comparative
studies are required to unveil its biological functions. In order to ascertain the …