Enalapril: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and congestive heart failure

PA Todd, RC Heel - Drugs, 1986 - Springer
Synopsis: Enalapril maleate 1 is an orally active angiotensin-converting enzyme inhibitor. It
lowers peripheral vascular resistance without causing an increase in heart rate. Enalapril 10 …

An overview of the clinical pharmacology of enalapril.

RO Davies, HJ Gomez, JD Irvin… - British journal of clinical …, 1984 - Wiley Online Library
Enalapril maleate is a prodrug which when administered orally is hydrolysed to release the
active converting enzyme inhibitor enalaprilat. Enalapril maleate is 60% absorbed and 40 …

[HTML][HTML] Anthracycline-induced cardiotoxicity: A multicenter randomised trial comparing two strategies for guiding prevention with enalapril: The International …

D Cardinale, F Ciceri, R Latini, MG Franzosi… - European journal of …, 2018 - Elsevier
Background Troponin changes over time have been suggested to allow for an early
diagnosis of cardiac injury ensuing cancer chemotherapy; cancer patients with troponin …

Enalapril maleate and a lysine analogue (MK‐521): disposition in man.

EH Ulm, M Hichens, HJ Gomez, AE Till… - British journal of …, 1982 - Wiley Online Library
1 The disposition of two angiotensin converting‐enzyme inhibitor drugs was studied in
normal volunteers. One drug was enalapril maleate (MK‐421), which requires in vivo …

Determinants of angiotensin II generation during converting enzyme inhibition.

L Juillerat, J Nussberger, J Menard, V Mooser… - …, 1990 - Am Heart Assoc
The reaction of the renin-angiotensin system to acute angiotensin converting enzyme
inhibition was investigated in a single-blind, crossover study in nine normal volunteers …

Lisinopril: a preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and congestive heart failure

SG Lancaster, PA Todd - Drugs, 1988 - Springer
Synopsis Lisinopril is an orally active angiotensin-converting enzyme (ACE) inhibitor which
at dosages of 20 to 80mg once daily is effective in lowering blood pressure in all grades of …

Quantification of pharmaceutical compounds in tissue and plasma samples using selective ion accumulation with multiple mass isolation windows

Z Liang, BM Prentice - Journal of Mass Spectrometry, 2023 - Wiley Online Library
Quantification of pharmaceutical compounds using matrix‐assisted laser
desorption/ionization (MALDI) mass spectrometry (MS) is an alternative to traditional liquid …

Enalapril: a review of human pharmacology

HJ Gomez, VJ Cirillo, JD Irvin - Drugs, 1985 - Springer
Enalapril, an orally-active, long-acting, nonsulphydryl angiotensin-converting enzyme (ACE)
inhibitor, is extensively hydrolysed in vivo to enalaprilat, its bioactive form. Bioactivation …

Clinical pharmacokinetics of the newer ACE inhibitors: a review

JG Kelly, K O'Malley - Clinical pharmacokinetics, 1990 - Springer
The orally active angiotensin-converting inhibitors (ACE inhibitors) such as captopril and
enalapril represent a significant therapeutic advance in the treatment of hypertension and …

Clinical pharmacokinetics of the angiotensin converting enzyme inhibitors: a review

SH Kubo, RJ Cody - Clinical pharmacokinetics, 1985 - Springer
The angiotensin converting enzyme inhibitors are an important therapeutic advance in the
treatment of patients with hypertension and congestive heart failure. In addition, they are …