Small non-coding RNA therapeutics for cardiovascular disease
AM Shah, M Giacca - European heart journal, 2022 - academic.oup.com
Novel bio-therapeutic agents that harness the properties of small, non-coding nucleic acids
hold great promise for clinical applications. These include antisense oligonucleotides that …
hold great promise for clinical applications. These include antisense oligonucleotides that …
Oncogenic roles of small nucleolar RNA host gene 7 (SNHG7) long noncoding RNA in human cancers and potentials
S Najafi, S Ghafouri-Fard, BM Hussen… - Frontiers in cell and …, 2022 - frontiersin.org
Long noncoding RNAs (lncRNAs) are a class of noncoding transcripts characterized with
more than 200 nucleotides of length. Unlike their names, some short open reading frames …
more than 200 nucleotides of length. Unlike their names, some short open reading frames …
Plant long non-coding RNAs: identification and analysis to unveil their physiological functions
E Domínguez-Rosas, MÁ Hernández-Oñate… - Frontiers in Plant …, 2023 - frontiersin.org
Eukaryotic genomes encode thousands of RNA molecules; however, only a minimal fraction
is translated into proteins. Among the non-coding elements, long non-coding RNAs …
is translated into proteins. Among the non-coding elements, long non-coding RNAs …
The long non-coding RNA nostrill regulates transcription of Irf7 through interaction with NF-κB p65 to enhance intestinal epithelial defense against Cryptosporidium …
The cells of the intestinal epithelium establish the frontline for host defense against
pathogens in the gastrointestinal tract and play a vital role in the initiation of the immune …
pathogens in the gastrointestinal tract and play a vital role in the initiation of the immune …
Exploration of the Noncoding Genome for Human-Specific Therapeutic Targets—Recent Insights at Molecular and Cellular Level
W Poller, S Sahoo, R Hajjar, U Landmesser… - Cells, 2023 - mdpi.com
While it is well known that 98–99% of the human genome does not encode proteins, but are
nevertheless transcriptionally active and give rise to a broad spectrum of noncoding RNAs …
nevertheless transcriptionally active and give rise to a broad spectrum of noncoding RNAs …
Rapid macrosatellite evolution promotes X-linked hybrid male sterility in a feline interspecies cross
KR Bredemeyer, CM Seabury… - Molecular biology …, 2021 - academic.oup.com
The sterility or inviability of hybrid offspring produced from an interspecific mating result from
incompatibilities between parental genotypes that are thought to result from divergence of …
incompatibilities between parental genotypes that are thought to result from divergence of …
Long Non-Coding RNAs in Cryptococcus neoformans: Insights Into Fungal Pathogenesis
MC Kalem, JC Panepinto - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Long non-coding RNAs (lncRNAs) are highly expressed and can modulate multiple cellular
processes including transcription, splicing, translation, and many diverse signaling events …
processes including transcription, splicing, translation, and many diverse signaling events …
In Silico Identification of Potential Quadruplex Forming Sequences in LncRNAs of Cervical Cancer
Long non-coding RNAs (lncRNAs) have emerged as auxiliary regulators of gene expression
influencing tumor microenvironment, metastasis and radio-resistance in cancer. The …
influencing tumor microenvironment, metastasis and radio-resistance in cancer. The …
Long non-coding RNAs associated with infection and vaccine-induced immunity
The immune system responds to infection or vaccination through a dynamic and complex
process that involves several molecular and cellular factors. Among these factors, long non …
process that involves several molecular and cellular factors. Among these factors, long non …
Molecular cloning, expression and cellular localization of two long noncoding RNAs (mLINC-RBE and mLINC-RSAS) in the mouse testis
Long noncoding RNAs (lncRNAs) are transcribed in complex, overlapping, sense-and
antisense orientations from intronic and intergenic regions of mammalian genomes …
antisense orientations from intronic and intergenic regions of mammalian genomes …