Onchocerciasis elimination: progress and challenges

T Lakwo, D Oguttu, T Ukety, R Post… - Research and Reports …, 2020 - Taylor & Francis
Onchocerciasis is a parasitic infection caused by the filarial nematode Onchocerca volvulus
and transmitted through the bites of black flies of the genus Similium that breed in rivers and …

The prevalence of onchocerciasis in Africa and Yemen, 2000–2018: a geospatial analysis

CA Schmidt, EA Cromwell, E Hill, KM Donkers… - BMC medicine, 2022 - Springer
Background Onchocerciasis is a disease caused by infection with Onchocerca volvulus,
which is transmitted to humans via the bite of several species of black fly, and is responsible …

Onchocerciasis (river blindness)–more than a century of research and control

NW Brattig, RA Cheke, R Garms - Acta Tropica, 2021 - Elsevier
This review summarises more than a century of research on onchocerciasis, also known as
river blindness, and its control. River blindness is an infection caused by the tissue filaria …

[HTML][HTML] Elimination of transmission of onchocerciasis (river blindness) with long-term ivermectin mass drug administration with or without vector control in sub …

N Mutono, MG Basáñez, A James, WA Stolk… - The Lancet Global …, 2024 - thelancet.com
Background WHO has proposed elimination of transmission of onchocerciasis (river
blindness) by 2030. More than 99% of cases of onchocerciasis are in sub-Saharan Africa …

Changes in epilepsy burden after onchocerciasis elimination in a hyperendemic focus of western Uganda: a comparison of two population-based, cross-sectional …

N Gumisiriza, C Kaiser, G Asaba, H Onen… - The Lancet Infectious …, 2020 - thelancet.com
Background In 1994, prevalence and incidence of epilepsy were high in the Itwara
onchocerciasis focus (western Uganda), and cases of nodding and Nakalanga syndrome …

Prevalence and incidence of nodding syndrome and other forms of epilepsy in onchocerciasis-endemic areas in northern Uganda after the implementation of …

N Gumisiriza, F Mubiru, JN Siewe Fodjo… - Infectious Diseases of …, 2020 - Springer
Background Around 2007, a nodding syndrome (NS) epidemic appeared in onchocerciasis-
endemic districts of northern Uganda, where ivermectin mass distribution had never been …

Reaching the last mile: main challenges relating to and recommendations to accelerate onchocerciasis elimination in Africa

G Gebrezgabiher, Z Mekonnen… - Infectious diseases of …, 2019 - mednexus.org
Background: Onchocerciasis (river blindness), caused by the filarial worm species
Onchocerca volvulus, is a serious vector-borne neglected tropical disease (NTD) of public …

The burden of skin disease and eye disease due to onchocerciasis in countries formerly under the African Programme for Onchocerciasis Control mandate for 1990 …

NVS Vinkeles Melchers, WA Stolk… - PLoS Neglected …, 2021 - journals.plos.org
Background Onchocerciasis (“river blindness”) can cause severe morbidity, including vision
loss and various skin manifestations, and is targeted for elimination using ivermectin mass …

The role of the Maridi Dam in causing an onchocerciasis-associated epilepsy epidemic in Maridi, South Sudan: an epidemiological, sociological, and entomological …

TL Lakwo, S Raimon, M Tionga, JN Siewe Fodjo… - Pathogens, 2020 - mdpi.com
Background: An epilepsy prevalence of 4.4% was documented in onchocerciasis-endemic
villages close to the Maridi River in South Sudan. We investigated the role of the Maridi dam …

What does the COVID-19 pandemic mean for the next decade of onchocerciasis control and elimination?

JID Hamley, DJ Blok, M Walker, P Milton… - Transactions of The …, 2021 - academic.oup.com
Background Mass drug administration (MDA) of ivermectin for onchocerciasis has been
disrupted by the coronavirus disease 2019 (COVID-19) pandemic. Mathematical modelling …